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Finasteride doesn't improve survival in LNCaP tumor model during off-cycle of therapy.

Combining different treatments may be needed to effectively manage chronic prostatitis.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Abietic acid from pine resin can effectively inhibit testosterone 5α-reductase.

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

The apelinergic system might protect the heart from damage caused by doxorubicin.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.

Lovastatin doesn't improve lower urinary tract symptoms treatment.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

Finasteride may cause long-lasting sexual side effects.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Liposomes improve finasteride delivery for hair loss treatment, making it a promising option for topical use.

Finasteride may worsen infertility in men with existing issues, but stopping it can improve sperm health.

Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Long-term use of dutasteride can cause permanent erectile dysfunction in rats.

Androgen receptors found in monkey scalps, similar to humans, affect hair growth.

Human scalp hair follicles can be used to study how prolactin affects hair growth and cell death.

Finasteride reduces melanin production, possibly treating hyperpigmentation and melanoma, but needs more safety research.

Finasteride 1-mg doesn't harm sperm or pregnancy chances.

Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.

Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.

The developed model can predict effective 5-alpha-reductase enzyme inhibitors.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

Animal research has greatly advanced dermatology.