275 citations
,
March 1999 in “Journal of The American Academy of Dermatology” Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.
252 citations
,
January 2008 in “Trends in Endocrinology and Metabolism” Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.
210 citations
,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.
176 citations
,
January 2003 in “Journal of Investigative Dermatology” Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.
152 citations
,
December 2003 in “Micron” As people age, their hair follicles produce less pigment, leading to gray and white hair, due to factors like reduced enzyme activity and damage to melanocyte DNA.
150 citations
,
April 2013 in “Dermato-endocrinology” Estrogen therapy can reduce skin aging but has cancer risks.
127 citations
,
January 2015 in “Journal of Biological Rhythms” The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.
112 citations
,
July 1998 in “Journal of Investigative Dermatology” Ruby laser pulses best destroy hair follicles during the growth phase and effectiveness varies with laser intensity; melanin is key for targeting, and timing treatments can improve results.
106 citations
,
July 2013 in “Advances in wound care” UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.
96 citations
,
January 1997 in “Clinics in Dermatology” Pregnancy can cause skin pigmentation, stretch marks, and changes in hair, nails, and sweat glands, with most resolving after birth.
67 citations
,
September 2003 in “Journal of cutaneous pathology” Skin problems are very common in people with end-stage kidney disease.
59 citations
,
April 2016 in “Cell Reports” EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.
53 citations
,
November 1997 in “Journal of Forensic Sciences” Darker hair in guinea pigs holds more codeine than lighter hair.
47 citations
,
June 1996 in “International Journal of Legal Medicine” Hair analysis for drugs needs a better understanding of how drugs enter hair, considering factors like hair structure and pigmentation.
39 citations
,
January 2008 in “Journal of Endocrinology” SCF and c-Kit decrease in AGA hair follicles, possibly affecting hair pigmentation and growth.
38 citations
,
June 2017 in “The Journal of Dermatology” Aging in hair follicle stem cells leads to hair graying, thinning, and loss.
34 citations
,
January 2014 in “International Journal of Trichology” Polarized dermoscopy is slightly better than nonpolarized for diagnosing hair disorders, with each method having its own strengths.
29 citations
,
January 2021 in “Journal of Investigative Dermatology” Fat under the skin releases HGF which helps hair grow and gain color.
29 citations
,
January 2013 in “International Journal of Medical Sciences” Wnt10b helps hair follicle cells mature and produce pigment.
22 citations
,
February 2008 in “Journal of Dermatological Science” EPR spectroscopy showed that spontaneous hair growth results in thicker skin and less pigmented hair than depilation-induced growth.
21 citations
,
November 2011 in “Veterinary Pathology” Mouse skin color ranges from pink to black, depending on their hair growth cycle.
20 citations
,
February 2023 in “Biology” Innovative cosmetics could safely change hair color by targeting biological hair pigmentation processes.
19 citations
,
January 2014 in “Facial plastic surgery” Dermabrasion improves skin appearance by removing the top layer to promote healing.
19 citations
,
May 2005 in “Archives of Environmental & Occupational Health” All immigrant workers in the study had skin problems, with fungal nail infections, athlete's foot, and acne or folliculitis being most common, affecting their quality of life, yet they didn't seek medical help.
19 citations
,
May 1984 in “Digestive diseases and sciences” A young woman's Cronkhite-Canada syndrome improved on its own after she gave birth.
18 citations
,
January 2020 in “Ecology and evolution” Genes related to pigmentation, body rhythms, and behavior change during hares' seasonal coat color transition, with a common genetic mechanism in two hare species.
17 citations
,
December 2015 in “International Journal of Cosmetic Science” Visible light can improve skin disorders and hair loss, but more research is needed to understand long-term effects.
12 citations
,
February 2025 in “Scientific Reports” MSC-EVs and UCB-EVs improve skin wound healing and reduce scarring.
12 citations
,
May 2023 in “EMBO reports” High mTORC1 activity slows hair growth and causes it to lose color.
10 citations
,
November 2010 in “Pigment Cell & Melanoma Research” Only skin melanocytes, not other types, can color hair in mice.