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Researchers developed reliable models to predict how well certain compounds bind to androgen receptors, emphasizing the importance of atomic electronegativity.

New steroids were effective in blocking male hormone receptors in hamster prostates.

Lack of TrkC receptor delays hair follicle development.

Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.

A single amino acid change in the vitamin D receptor can disrupt its function and lead to hair loss.

ARQ-234, a protein designed to treat atopic dermatitis, shows increased effectiveness in early testing.

Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.

FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.

Mutations at Val-889 and Arg-752 disrupt key interactions in the androgen receptor, affecting its function.

Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.

The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.

Spironolactone reduces the number of androgen receptor sites in rat skin by blocking them with its metabolite.

Some cannabinoid derivatives may be more effective than current drugs at targeting proteins relevant to prostate cancer treatment.

Mutations at Val-889 and Arg-752 disrupt key interactions in androgen receptor dimerization.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

New compounds were made and tested, with compound 6 showing potential for treating prostate-related diseases.

Vinblastine and its metabolites may cause nausea and hair loss by binding to specific receptors and could lead to better chemotherapy drugs with fewer side effects.

Parsley contains compounds that might be good for treating hair loss.

EGF receptors are crucial for skin cell growth and decrease with age.

A new protein was made to detect specific skin cell growth receptors and worked in normal skin but not in skin cancer cells.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

Scientists found a new type of skin cell that could help with skin repair and these cells work better with a certain protein.

Cells from balding scalps have more androgen receptors than cells from non-balding scalps.

A point mutation in the androgen receptor gene causes complete androgen insensitivity.

Red deer only have androgen receptors in neck hair cells for mane growth during breeding season.