research America - A Diversity of Life Styles.
The drug showed promise in treating renal cell carcinoma with manageable side effects.
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390-420 / 1000+ resultsresearch Pertinence d’une chimioprévention à partir de l’étude PCPT
Finasteride shows promise for preventing prostate cancer, but more research is needed.
research Molecular Interactions of New Pregnenedione Derivatives
The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.
research Inhibition of a signaling modality within the gp130 receptor enhances tissue regeneration and mitigates osteoarthritis
Blocking a certain signal in the gp130 receptor can improve tissue healing and lessen osteoarthritis symptoms.
research Hereditary 1,25-Dihydroxyvitamin D Resistant Rickets due to a Mutation Causing Multiple Defects in Vitamin D Receptor Function
A specific gene mutation causes vitamin D resistance, but certain vitamin D analogs might help.
research 1406 DETECTION OF MEMBRANE ANDROGEN-BINDING SITE IN LIVING RAT PROSTATE AND EVALUATION OF ITS ROLE IN PROSTATE BLOOD FLOW REGULATION
The research found that androgens help control blood flow in the rat prostate through a specific binding site.
research Enzyme-linked immunosorbent assays for doping control of 5α-reductase inhibitors finasteride and dutasteride
New tests detect finasteride and dutasteride in urine quickly and easily.
research Advancing Design Strategy of PROTACs for Cancer Therapy
PROTACs show promise for cancer treatment, but designing them effectively is challenging.
research Androgen receptor signaling as a new target for intervention in acute myeloid leukemia
Targeting androgen receptor signaling may improve acute myeloid leukemia treatment.
research Feronia: A Malectin-Like Domain-Containing Receptor Kinase in Arabidopsis Thalina
FERONIA is crucial for plant growth, pollen tube reception, and sugar signaling.
research Characterisation, genomic organisation, expression and function of the mEphA1 receptor Tyrosine Kinase
mEphA1 receptor tyrosine kinase is important for skin and hair development and may play a role in certain diseases.
research Polymer conjugated retinoids for controlled transdermal delivery
A new method allows for controlled, long-lasting delivery of retinoic acid through the skin with fewer side effects.
research The Role of Vitamin D and its Receptor in Skin and Hair Follicle Biology
Vitamin D and its receptor are crucial for skin and hair health.
research Synthesis and in Vitro Evaluation of 4-Substituted N-(1,1-Dimethylethyl)-3-oxo-4-androstene-17.beta.-carboxamides as 5.alpha.-Reductase Inhibitors and Antiandrogens
The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.
research Polymer conjugated retinoids for controlled transdermal delivery
A new method allows for controlled, long-lasting delivery of retinoic acid through the skin with less inflammation.
research A NIR-responsive PDA@RES core-shell nanoplatform accelerates chronic wound healing by remodeling mitochondrial homeostasis and reversing cellular senescence
A special treatment speeds up chronic wound healing by fixing cell energy issues and reversing aging in cells.
research The mineralocorticoid receptor plays a transient role in mouse skin development
The mineralocorticoid receptor temporarily affects mouse skin development, but the glucocorticoid receptor has a more lasting impact.
research A Prospective Observational Study for Assessment of Chemotherapy-Induced Adverse Drug Reactions in Cancer Patients
Females had more chemotherapy side effects than males, with many being preventable.
research Modulation of Androgen Receptor Transcriptional Activity
Androgen receptor activity is influenced by hormones, co-factors, modifications, and mutations.
research New insights into molecular signaling pathways and current advancements in prostate cancer diagnostics & therapeutics
New drugs and therapies targeting specific pathways show promise in treating advanced prostate cancer.
research Characterization of Rickets Type II Model Rats to Reveal Functions of Vitamin D and Vitamin D Receptor
The research showed that Vitamin D and its receptor are important for healthy bones and normal hair and skin in rats.
research Drug Repurposing Patent Applications July–September 2025
New drug uses show promise but need more research.
research CUTANEOUS T-CELL LYMPHOMA
The document concludes that DAB389-IL2 is promising for treating refractory cutaneous T-cell lymphoma, but more research is needed on its effectiveness and side effect management.
research P.1.g.019 RY-023, an inverse agonist at alpha5 GABAA receptors: the influence on spatial memory and spontaneous locomotor activity
RY-023, a specific drug, can improve early stage memory learning without affecting general activity in rats, but it's less effective for later learning stages and doesn't impact memory recall.
research Sensitive Bromatometric Determination Of Finasteride In Pharmaceuticals Based On Complex-Formation Reactions
Two accurate methods were developed to measure finasteride in tablets.
research In Silico Screening of DrugBank Compounds as Potential Inhibitors for Human Steroid 5α-Reductase 2 for Androgen-Related Diseases
Stiripentol shows promise as a potential treatment for androgen-related diseases but needs more testing.
research Drug Repurposing: Accelerating New Therapeutic Discoveries from Old Molecules (1990 – 2025)
Drug repurposing finds new uses for old drugs quickly and cheaply.
research Expression of retinoid nuclear receptor superfamily members in human hair follicles and its implication in hair growth.
RXR agonists may promote hair growth in humans.
research Design, synthesis, and biological activity of TLR7-based compounds for chemotherapy-induced alopecia
TLR7-based compounds may help manage chemotherapy-induced hair loss.
research Drug Repurposing - Hypothesis, Molecular Aspects and Therapeutic Applications
Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.