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ErbB2 signaling is crucial for skin cell growth and cancer development in mice.

Gene therapy in mice increased lifespan and improved health without causing cancer.

Non-viral delivery systems and stimuli-responsive nanoformulations can improve CRISPR-Cas9 gene therapy.

Mice with human-like EGFR had growth issues, skin defects, heart problems, and unusual bone development.

MPA increases cancer spread by boosting Eph A2 activity.

Ethosomes are effective, safe carriers for delivering drugs through the skin.

Human exosomes are effective for targeted treatments but face scalability issues, while plant exosomes are cost-effective for cosmetics.

Genetically modified sheep with more β-catenin grew more wool without changing the wool's length or thickness.

The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.

Mouse and human keratin 16 can both form filaments, with differences likely due to the tail domain, not the helical domain.

Activating Wnt signaling improves the efficiency and safety of creating stem cells.

Biomimetic synthetic vesicles could improve precision medicine by combining natural and synthetic benefits.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

17β-estradiol boosts APE1/Ref-1 secretion in cells and mice via a calcium-dependent pathway.

Human stem cells can turn into functional eye cells that might help treat retinal diseases.

Gene therapy shows promise for treating hair loss by targeting hair follicles.

Keratins K6 and K16 are expressed more freely in regenerating mouse skin than K1 and K10.

Gene therapy shows promise for improving wound healing, but more research is needed for human use.

A new protein was made to detect specific skin cell growth receptors and worked in normal skin but not in skin cancer cells.

A new method helps grow skin cells from humans and mice more easily and quickly.

Extracellular vesicles show promise for treating diseases but face challenges in development and regulation.

The developed system could effectively treat hair loss and promote hair growth.

EV-based drug delivery shows promise but faces challenges in standardization and scalability.

DermaCult™ Keratinocyte Expansion Medium allows human skin cells to grow longer while keeping their ability to develop properly.

Gene therapy helped rats with a specific type of rickets grow hair without severe inflammation.

The study found a specific peptide that helps detect TGase 3 activity in skin and hair follicles.

High levels of ODC and a mutant Ha-ras gene cause tumors in mice.

PROTACs offer new ways to treat hard-to-target diseases, with promising drugs for cancer in advanced trials.