86 citations
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July 2020 in “International Journal of Molecular Sciences” Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.
71 citations
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February 2020 in “Journal of Translational Medicine” Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.
70 citations
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August 2020 in “Nanomaterials” Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.
68 citations
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March 2019 in “Advanced Healthcare Materials” Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.
68 citations
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May 2018 in “PLOS Biology” Cyclosporine A may help treat hair loss by blocking a protein that inhibits hair growth.
65 citations
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June 2021 in “Frontiers in Pharmacology” Targeting abnormal lung fluid metabolism could reduce COVID-19 deaths and ventilator use.
64 citations
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August 2007 in “Artificial Organs” PHBV nanofiber matrices help wounds heal faster when used with hair follicle cells.
59 citations
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March 2020 in “Journal of Biomedical Science” Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.
54 citations
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August 2019 in “Bioscience trends” Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.
53 citations
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April 2014 in “Experimental Dermatology” Wnt10b makes hair follicles bigger, but DKK1 can reverse this effect.
52 citations
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October 2012 in “Journal of Dermatological Science” The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.
50 citations
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November 2010 in “Plastic and Reconstructive Surgery” Botox increased hair count in men with baldness and might work by improving scalp blood flow.
49 citations
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November 2014 in “Journal of Medicinal Food” Red Ginseng Extract may help human hair grow by activating growth pathways and blocking negative effects of certain hormones.
48 citations
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February 2016 in “Scientific Reports” Researchers created rat liver stem cells that could help repair liver failure in rats and may be useful for studying human liver diseases.
42 citations
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February 2018 in “International Journal of Molecular Sciences” Minoxidil boosts hair growth by triggering growth factor release from specific stem cells.
42 citations
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October 2011 in “Seminars in Cell & Developmental Biology” Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.
36 citations
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August 2011 in “Journal of Controlled Release” Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.
33 citations
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January 2018 in “The International Journal of Developmental Biology” Cell aging can be both good and bad for tissue repair.
30 citations
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February 2022 in “Stem Cell Reviews and Reports” Stem cell treatments may improve burn wound healing.
28 citations
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February 2016 in “F1000Research” Understanding glycans and enzymes that alter them is key to controlling hair growth.
28 citations
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January 2016 in “Vitamins and hormones” Thymosin β4 helps improve skin healing and reduce scarring.
28 citations
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December 2012 in “The American Journal of Cosmetic Surgery” Proteins from stem cells improved hair growth in patients with hair loss.
28 citations
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October 2011 in “International Journal of Molecular Medicine” Adenosine helps hair grow longer and stronger by boosting certain growth factors and signaling pathways.
27 citations
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March 2019 in “PLoS ONE” Thyroxine (T4) may help heal skin wounds by promoting new skin and blood vessel growth.
26 citations
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December 2016 in “Pharmacology & Therapeutics” New drugs for heart disease may be developed from molecules secreted by stem cells.
25 citations
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November 2014 in “Ageing Research Reviews” Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
23 citations
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May 2015 in “Science China Life Sciences” The microenvironment controls adult stem cells' behavior and fate.
20 citations
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October 2018 in “Aesthetic Plastic Surgery” PRP shows promise for improving facial wrinkles, skin elasticity, and hair growth, but more research is needed to standardize its use and understand its effects.
20 citations
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February 2017 in “International Journal of Dermatology” Platelet-based therapies using a patient's own blood show promise for skin and hair regeneration but require more research for confirmation.
19 citations
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May 2020 in “Cells” Substance from human umbilical cord blood cells promotes hair growth.