research Identification of drug-specific public TCR driving severe cutaneous adverse reactions
Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.
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research Bioengineering a 3D integumentary organ system from iPS cells using an in vivo transplantation model
Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.
research Understanding Cancer Cells of Origin in Cutaneous Tumors
The document concludes that identifying the specific cells where skin cancers begin is important for creating better prevention, detection, and treatment methods.
research 1α,25-Dihydroxyvitamin D3 Modulates the Hair-Inductive Capacity of Dermal Papilla Cells: Therapeutic Potential for Hair Regeneration
Vitamin D3 can help improve hair growth by enhancing the function of specific skin cells and could be useful in hair regeneration treatments.
research Rapid Genetic Analysis of Epithelial-Mesenchymal Signaling During Hair Regeneration
The method quickly analyzes hair growth genes and shows that blocking Smo in skin cells stops hair growth.
research Australasian Society for Dermatology Research Meeting, May 2006
The meeting highlighted the genetic basis of female pattern hair loss and various skin health insights.
research Expansion of Hair Follicle Stem Cells Sticking to Isolated Sebaceous Glands to Generate in Vivo Epidermal Structures
Sebaceous glands can help harvest hair follicle stem cells to regenerate skin and hair.
research Functionalised-biomatrix for wound healing and cutaneous regeneration: future impactful medical products in clinical translation and precision medicine
The document concludes that more research is needed on making and understanding biomaterial scaffolds for wound healing.
research Recessive Epidermolysis Bullosa Simplex Phenotype Reproduced in Vitro
Fibroblasts from healthy donors can prevent changes seen in recessive epidermolysis bullosa simplex.
research Plasma-Polymerised Antibacterial Coating of Ovine Tendon Collagen Type I (OTC) Crosslinked with Genipin (GNP) and Dehydrothermal-Crosslinked (DHT) as a Cutaneous Substitute for Wound Healing
The GNP crosslinked scaffold with antibacterial coating is effective for rapid wound healing and infection prevention.
research Fully functional hair follicle organ regeneration using organ-inductive potential stem cells with an accessory mesenchymal cell population in an in vitro culture system
Scientists successfully regenerated functional hair follicles using specific stem cells and mesenchymal cells.
research Novel tissue mechanics-guided cellular flows drive the formation of feather follicles
Feather follicles form through specific cellular flows and mechanical changes in the skin.
research TCF/Lef1 activity controls establishment of diverse stem and progenitor cell compartments in mouse epidermis
TCF/Lef1 activity is essential for proper skin cell development and renewal.
research Concise Review: Human Dermis as an Autologous Source of Stem Cells for Tissue Engineering and Regenerative Medicine
Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.
research Dermal Papilla Cells: From Basic Research to Translational Applications
Dermal papilla cells can help regrow hair and are promising for hair loss treatments.
research Small molecules facilitate single factor-mediated sweat gland cell reprogramming
Small molecules can help turn skin cells into sweat gland-like cells for potential skin repair.
research Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells
Adult mouse skin contains stem cells that can create new hair, skin, and oil glands.
research Epidermal mammalian target of rapamycin complex 2 controls lipid synthesis and filaggrin processing in epidermal barrier formation
mTORC2 is crucial for healthy skin barrier by regulating lipids and filaggrin.
research Structural mechanism of TRPV3 channel inhibition by the plant‐derived coumarin osthole
Osthole inhibits the TRPV3 channel by binding to specific sites, potentially aiding drug development for skin diseases and cancers.
research Mechanisms of proton inhibition and sensitization of the cation channel TRPV3
Acid can block TRPV3 from outside the cell but boost its function from inside.
research Culture Strategy Determines the Differentiation Status of Sweat Gland Cells
3D culture better preserves sweat gland cell identity than 2D culture.
research Cells, growth factors and biomaterials used in tissue engineering for hair follicles regeneration
Advancements in tissue engineering show promise for hair follicle regeneration to treat hair loss.
research Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis
Sox2-positive cells determine specific hair follicle types in mammals.
research Type XVII collagen coordinates proliferation in the interfollicular epidermis
Type XVII collagen helps control skin cell growth and could be a target for anti-aging treatments.
research Organoid technology for tissue engineering
Organoid technology helps create mini-organs for studying diseases and testing drugs.
research Innate type 2 immunity controls hair follicle commensalism by Demodex mites
Type 2 immunity helps control mite growth in hair follicles, preventing damage.
research Monovalent antibody-conjugated lipid-polymer nanohybrids for active targeting to desmoglein 3 of keratinocytes to attenuate psoriasiform inflammation
The targeted nanohybrids effectively reduced psoriasis symptoms and improved skin health.
research Large-Scale Preparation of Hair Follicle Germs Using a Microfluidic Device
A new method using a microfluidic device can prepare hair follicle germs efficiently for potential use in hair loss treatments.
research Reawakening GDNF's regenerative past in mice and humans
Activating the GDNF-GFRα1-RET signaling pathway could potentially promote skin and limb regeneration in humans and could be used to treat hair loss and promote wound healing.
research Maintenance of Barrier Tissue Integrity by Unconventional Lymphocytes
Unconventional lymphocytes are important for quick immune responses and healing of skin and mucosal barriers.