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Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Testosterone boosts red blood cell production and changes iron metabolism without needing dihydrotestosterone.

Testosterone can cause acne and male-pattern baldness, affects hair growth in men and women, and makes male skin more sensitive.

A 17-year-old female with adrenogenital syndrome produces very high levels of androgens, which prevent complete feminization despite high estrogen doses.

Men and women experience skin aging differently due to changes in sex hormone levels with age.

Testosterone reduces knee flexibility by affecting relaxin receptors.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Androgens increase growth factors in skin cells, which may lead to acne.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.

Epilepsy and certain epilepsy drugs can lead to reproductive problems in women, but changing medication might improve these issues.

Gene mutations can cause problems in male genital development.

Wait 3 months after COVID-19 before trying assisted reproduction and further research is needed on COVID-19's effects on male hormones and fertility.

5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.

Exogenous testosterone use may be linked to developing hidradenitis suppurativa.

Some common medications can harm male fertility, but many effects can be reversed.

Honokiol might help reduce male skin aging by maintaining testosterone levels.

DHT, a testosterone byproduct, causes male pattern baldness.

Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

Some sports supplements can cause health issues like mood swings, hair loss, and heart problems in men.

Finasteride effectively treats baldness but may cause sexual side effects.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

Testosterone reduces heart damage and inflammation after injury.

Ursolic acid can shrink the prostate and lower a hormone linked to prostate growth in rats.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Diphenyl ethers can potentially reduce excess oil production when applied on the skin, helping treat conditions like acne.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.