218 citations
,
January 2013 in “The Lancet Oncology” Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.
138 citations
,
June 2012 in “Genes & Development” Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.
81 citations
,
December 2009 in “Journal of Dermatological Science” Fat tissue stem cells may help increase hair growth.
34 citations
,
March 2001 in “Cleveland Clinic Journal of Medicine” Manage hair shedding by identifying triggers, possibly using supplements or medications, and tracking with a health calendar.
30 citations
,
May 2018 in “Experimental Dermatology” The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.
23 citations
,
January 2002 in “Journal of Cutaneous Medicine and Surgery” Finasteride helps hair growth by decreasing cell death in hair follicles.
21 citations
,
January 2002 in “Journal of Cutaneous Medicine and Surgery” Finasteride affects hair growth by changing caspase and XIAP levels, potentially treating hair diseases.
12 citations
,
October 2020 in “Scientific Reports” Necrostatin-1s can promote hair growth and may help treat hair loss.
10 citations
,
January 2019 in “Biomarker Insights” Scalp cooling to prevent hair loss from chemotherapy works for some but not all, and studying hair damage markers could improve prevention and treatment.
8 citations
,
April 2023 in “Cureus” Stem cells could be a better treatment for hair loss by reactivating dormant hair follicles.
3 citations
,
January 2019 in “Advances in stem cells and their niches” Dermal papilla cells are key for hair growth and color, influencing hair type and size, and their interaction with stem cells could help treat hair loss and color disorders.
3 citations
,
October 2007 in “Expert Review of Dermatology” Hair ages due to various factors and treatments like minoxidil and finasteride can help, but more research and better public awareness are needed.
2 citations
,
November 2002 in “Dermatologic Surgery” The authors' 10-year experience shows that a personalized approach to hair restoration surgery, using various techniques, leads to natural results and high patient satisfaction.
1 citations
,
September 2013 in “Elsevier eBooks” Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.
December 2024 in “Highlights in Science Engineering and Technology” Stem cells show promise for hair regrowth, but challenges remain.
September 2023 in “Nature communications” Alk1 in specific cells is crucial for proper nerve branching and hair function.
February 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” The gene Prss53 affects hair shape and bone development in rabbits.
November 2002 in “Dermatologic Surgery” Scalp reduction gives the most natural result for significant crown baldness, despite potential complications, and a systematic approach to surgical hair restoration results in few complications and high graft survival.
37 citations
,
January 2009 in “Dermatology” Healthy women tend to lose more hair in July and April, and the least in February.
7 citations
,
January 1981 in “Springer eBooks” The document concludes that hair biology is complex and there are still unanswered questions about hair loss and follicle changes.
98 citations
,
June 2008 in “Human mutation” A genetic change in the EDAR gene causes the unique hair traits found in East Asians.
32 citations
,
December 2013 in “Biological & Pharmaceutical Bulletin” Rice bran extract can potentially treat hair loss by promoting hair growth and increasing the number of hair follicles.
May 2023 in “Frontiers in chemistry” Zolpidem shows up in hair from the top back of the head after one dose and fades over time, suggesting it gets into hair through blood and sweat.
January 2000 in “BioScience” The document concludes that understanding hair biology is key to treating hair disorders, with gene therapy showing potential as a future treatment.
113 citations
,
September 2005 in “Journal of Investigative Dermatology” Applying a special compound can promote hair growth without harmful side effects.
87 citations
,
July 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” Human beard hair medulla contains a unique and complex mix of keratins not found in other human tissues.
11 citations
,
June 2022 in “Frontiers in immunology” New protein changes may be involved in the immune attack on hair follicles in alopecia areata.
9 citations
,
January 2008 in “Acta histochemica et cytochemica” COX-2 levels change during the hair cycle and affect skin and hair growth.
6 citations
,
May 2022 in “Frontiers in physiology” Injecting CHIR-99021 into goose embryos improves feather growth by changing gene activity and energy processes.
2 citations
,
December 2023 in “Royal Society of Chemistry eBooks” Hair is a complex organ, and understanding its detailed structure and growth phases is crucial for analyzing substances within it.