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Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

Three specific 4-azasteroid-2-oximes showed strong enzyme inhibition, but less than finasteride.

Blocking the enzyme that turns testosterone into DHT can safely and effectively treat enlarged prostate.

Male pattern baldness is likely caused by multiple genes, not just 5α-reductase genes.

5α-reductase inhibitors may prevent prostate cancer but could also raise the risk of more severe cancers.

Finasteride safely lowers DHT levels without affecting testosterone.

Testosterone's muscle-building effects do not require its conversion to DHT.

Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

5α-reductase inhibitors may cause persistent sexual dysfunction and depression, needing more research on long-term effects.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.

Lack of 5α-Reductase type 1 can lead to insulin resistance and liver problems.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.

New compounds called benzoquinolinones may treat conditions linked to excess DHT.

Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

Some Thai plants, especially Carthamus tinctorius, could help prevent hair loss and promote hair growth without adverse effects.

Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.

Finasteride and dutasteride effectively treat hair loss, but may cause side effects like sexual dysfunction and depression.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

5alpha-reductase inhibitors like finasteride and dutasteride effectively treat BPH by reducing DHT, offering symptom relief and potential future uses.