January 2013 in “Hair transplant forum international” Minoxidil and finasteride are effective for male hair loss; minoxidil also helps female hair loss, with some treatments needing more research.
April 2005 in “Aktuelle Dermatologie” Shampoos have evolved to address individual hair and scalp needs, and treatments like Minoxidil and Finasteride help with hair loss.
March 2005 in “Journal of The American Academy of Dermatology” The two lotions used day and night may be a good alternative to minoxidil for hair loss treatment with better cosmetic effects and tolerance.
March 2005 in “Journal of The American Academy of Dermatology” Two cosmetic lotions used day and night may be a good alternative to minoxidil for hair loss treatment with better cosmetic effects and tolerance.
January 2005 in “Urologia Journal” 5αR inhibitors help slow early prostate cancer cell growth, suggesting combined treatments are needed.
3 citations
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January 2021 in “Skin appendage disorders” Hair loss can occur about 4 weeks after scalp surgery but usually grows back within 3 months without treatment.
20 citations
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December 2003 in “Journal of Cosmetic and Laser Therapy” An 800nm diode laser safely and effectively reduces hair for about 8 months, with most patients satisfied and few side effects.
70 citations
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June 1998 in “Polymer” Permanent waving damages hair by disrupting its keratin structure.
35 citations
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October 2004 in “Biology of Reproduction” PNU157706 reduced rat sperm movement and fertility without affecting offspring health.
23 citations
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October 2018 in “Australasian Journal of Dermatology” The current understanding of frontal fibrosing alopecia involves immune, genetic, hormonal factors, and possibly environmental triggers, but more research is needed for effective treatments.
193 citations
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August 1985 in “Endocrinology” Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.
41 citations
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July 2012 in “Stem Cells and Development” Low-dose UVB light improves hair growth effects of certain stem cells by increasing reactive oxygen species.
1 citations
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January 2021 in “Acta Cirurgica Brasileira” Dutasteride and finasteride cause kidney damage, with dutasteride being more harmful.
March 2014 in “The Journal of Urology” Finasteride increases CD8+ T cells in BPH tissues.
223 citations
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December 2010 in “The Journal of Sexual Medicine” Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.
219 citations
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January 2005 in “Plastic & Reconstructive Surgery” Surgical treatment can significantly reduce or eliminate migraine symptoms.
195 citations
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February 2007 in “The Journal of Clinical Endocrinology and Metabolism” Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.
184 citations
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January 2000 in “European Urology” Blocking the enzyme that turns testosterone into DHT can safely and effectively treat enlarged prostate.
165 citations
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December 2002 in “Molecular and Cellular Endocrinology” Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.
153 citations
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April 2009 in “Urology” Prostate cancer was a major health issue in 2009, especially for Black men, and targeting the 5alpha-reductase enzyme could help in its prevention and treatment.
147 citations
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April 1990 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride safely lowers DHT levels without affecting testosterone.
125 citations
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February 2007 in “Journal of the American Academy of Dermatology” Combining eflornithine cream with laser treatment removes facial hair better than laser alone.
97 citations
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April 2016 in “Andrology” Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.
90 citations
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July 2008 in “Dermatologic therapy” Lichen planopilaris is a chronic, scarring hair loss condition with no definitive cure, requiring accurate diagnosis and treatment to manage symptoms.
76 citations
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April 2013 in “PLoS ONE” Chronic stress can cause hair loss by increasing oxidative stress, but antioxidants may help.
75 citations
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January 2014 in “Korean Journal of Urology” 5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.
70 citations
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August 1995 in “Fertility and Sterility” Finasteride reduces hairiness and androgen levels in women with unexplained excessive hair growth.
59 citations
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May 2014 in “Expert Opinion on Therapeutic Targets” The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.
47 citations
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September 2016 in “Reviews in endocrine and metabolic disorders” The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
45 citations
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September 2000 in “Archives of dermatology” The study found that the enzyme linked to acne is present in the same areas of both acne-affected and normal skin.