23 citations
,
September 2015 in “PLOS ONE” Mesenchymal stem cells, especially injected into the skin, heal wounds faster and better than chitosan gel or other treatments.
December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Aged individuals heal wounds less effectively due to specific immune cell issues.
141 citations
,
August 2017 in “Developmental Dynamics” The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.
44 citations
,
May 2008 in “Acta Zoologica” Keratinization in embryos helped vertebrates adapt to land by forming a protective skin barrier.
11 citations
,
October 2001 in “Tissue engineering” Cultured epithelium can form hair follicles when combined with dermal papillae.
20 citations
,
December 2013 in “PLoS ONE” β1 integrin is essential for the survival, growth, and movement of human epithelial progenitor cells.
31 citations
,
November 2022 in “Cold Spring Harbor Perspectives in Biology” Epithelial cells adapt and work together to heal skin wounds effectively.
52 citations
,
January 2023 in “Annual Review of Immunology” Immune-epithelial interactions are crucial for tissue repair, but unchecked can cause diseases.
4 citations
,
May 2014 in “Biochemical Society Transactions” Environmental cues can change the fate and function of epithelial cells, with potential for cell therapy.
92 citations
,
March 2016 in “Developmental Cell” Zebrafish skin regeneration relies on cell behaviors and reactive oxygen species, with antioxidants reducing and hydrogen peroxide increasing regeneration.
June 2026 in “Cell Regeneration” The olfactory epithelium can regenerate throughout life, aided by specific cells, genes, and new research methods.
130 citations
,
February 2005 in “Proceedings of the National Academy of Sciences” Corneal cells can transform into skin and hair cells through specific signals.
42 citations
,
September 1990 in “Journal of Investigative Dermatology” 158 citations
,
January 2009 in “The International Journal of Developmental Biology” Reptile scales help us understand the evolution of skin features like hair and feathers.
29 citations
,
April 2020 in “Journal of Tissue Engineering and Regenerative Medicine” The experiment showed that human skin grown in the lab started to form early hair structures when special cell clusters were added.
38 citations
,
January 2006 in “Journal of Cellular Biochemistry” Researchers isolated a new type of stem cell from mouse skin that can renew itself and turn into multiple cell types.
42 citations
,
October 2011 in “Seminars in Cell & Developmental Biology” Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.
August 1993 in “Journal of Dermatological Science” January 2006 in “Elsevier eBooks” Most vertebrates can regenerate skin, nails, and corneas, but only some can regenerate teeth and lenses.
December 2010 in “HAL (Le Centre pour la Communication Scientifique Directe)” The cornea develops independently of the lens, following its own default pathway.
20 citations
,
January 2001 in “Journal of Cutaneous Laser Therapy” Occlusive dressings speed up skin healing after CO2 laser resurfacing.
Retinoic acid can change skin development, like turning scales into feathers or forming glands.
Epimorphin helps shape and develop epithelial cells, like those in hair follicles.
128 citations
,
March 1996 in “Journal of Investigative Dermatology” 14 citations
,
April 1995 in “Transplantation” Human hair follicle cells can be used to help heal and replace skin.
De-epithelialization reduces complications in subcutaneous skin flap procedures.
85 citations
,
July 2012 in “Cold Spring Harbor perspectives in biology” The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
23 citations
,
January 2023 in “Journal of Developmental Biology” Reptile skin protects and prevents water loss, helping them adapt to land.
June 2022 in “Scientific Reports” Prevelex, a polyampholyte, can create a cell-repellent coating on microdevices, which can be useful in biomedical applications like hair follicle regeneration.
July 2025 in “Bulgarian Portal for Open Science” Granulation and epithelialization are crucial for healing large skin wounds.