42 citations
,
September 2007 in “The Journal of Clinical Endocrinology and Metabolism” The research found that polycystic ovary syndrome (PCOS) has two distinct types, with one having more severe hormone and insulin issues.
1 citations
,
January 1986 in “Journal of Steroid Biochemistry” Women with excessive hair growth or polycystic ovary disease may more often carry a gene variant for 21 hydroxylase deficiency.
18 citations
,
November 2012 in “Current opinion in urology” Finasteride and dutasteride are equally effective and safe for treating benign prostatic hyperplasia.
1 citations
,
October 2022 in “Adolescent Health, Medicine and Therapeutics” Gender-affirming therapy can cause skin issues like acne and hair loss in transgender adolescents, and more research is needed on its dermatological effects.
9 citations
,
March 1999 in “Der Hautarzt” Type 2 5α-reductase plays a key role in hair loss.
January 2013 in “Journal of Endocrinology and Diabetes Mellitus” Cushing syndrome often causes low testosterone and sexual issues in men.
32 citations
,
July 2016 in “PubMed” 5-alpha reductase inhibitors are generally safe but can cause sexual side effects and require patient education on risks.
Cyproterone acetate with ethynyl estradiol significantly improved acne and seborrhea in women, but was less effective for hair loss and excessive hair growth.
9 citations
,
October 2018 in “Medical Science Monitor” Lowering certain hormone levels improves treatment for hair loss in young men.
October 2020 in “Journal of the American Society of Nephrology” Drospirenone can hide symptoms of certain hormonal disorders, complicating diagnosis.
Androgenetic alopecia is not linked to higher risks of hypertension or hyperaldosteronism.
July 2024 in “Age and Ageing” Men taking dutasteride may have a higher risk of age-related macular degeneration.
87 citations
,
April 1973 in “Endocrinology” The chemicals 17βC and its methyl ester can block the effects of testosterone on hamster skin but not the effects of DHT.
36 citations
,
May 2017 in “The journal of sexual medicine” Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.
40 citations
,
March 1982 in “British Journal of Dermatology” Young women with diffuse hair loss may have low SHBG levels, which could lead to more active testosterone and contribute to their hair loss.
29 citations
,
January 2006 in “Clinical chemistry and laboratory medicine” SHBG binding properties are unchanged in male liver cirrhosis patients.
March 1997 in “Journal of Endocrinology/Journal of endocrinology” Excessive hair growth in women can be treated with medications like spironolactone and finasteride, and male-pattern baldness in women can be improved with similar treatments.
22 citations
,
September 2024 in “Human Reproduction Update” Androgen measurement helps diagnose PCOS, but accuracy varies, needing standard methods.
92 citations
,
October 2002 in “Journal of The American Academy of Dermatology” Finasteride improves hair loss in women with hyperandrogenism.
1 citations
,
July 2021 in “Clinical and Experimental Dermatology” Finasteride helps reduce hidradenitis suppurativa symptoms in females.
January 2004 in “Online Publication Service of Würzburg University (Würzburg University)” Women with PCOS have higher 5alpha-reductase activity, affecting steroid levels.
1 citations
,
June 2022 in “Frontiers in Neuroanatomy” Early hormones shape sex-specific differences in rat glands.
1 citations
,
June 2024 in “Revista Colombiana de Endocrinología Diabetes & Metabolismo” The risks of testosterone implants in women outweigh the benefits.
April 2026 in “Medicine Updates” 9 citations
,
December 1987 in “European journal of endocrinology” The treatment significantly reduced hair growth and male hormone levels in hirsute women.
September 2025 in “Consilium Medicum” 5α-reductase inhibitors help manage symptoms of benign prostatic hyperplasia and may also prevent prostate cancer and treat hair loss.
78 citations
,
December 2008 in “The Journal of Sexual Medicine” 5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction, but the exact reasons are unclear.
2 citations
,
May 2018 in “Diagnosis” A 68-year-old woman developed male traits due to a tumor in her ovary, which was removed, returning her hormone levels to normal.
20 citations
,
August 2019 in “Expert Opinion on Drug Safety” Some medications for bladder problems can cause memory issues or mood changes, and doctors should monitor these side effects.
12 citations
,
February 1997 in “British Journal of Dermatology” The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.