January 2026 in “Frontiers in Pharmacology” Certain drugs can cause male infertility, so fertility counseling and sperm preservation are advised.
July 2023 in “Media Dermato Venereologica Indonesiana” Less frequent intercourse is linked to higher erectile dysfunction.
July 2020 in “Vestnik urologii” The cause of post-finasteride syndrome is unclear and needs more research.
15 citations
,
March 2020 in “Anais Brasileiros De Dermatologia” Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.
September 2019 in “Reactions Weekly” Man experienced post-finasteride syndrome symptoms after using finasteride and dutasteride for hair loss.
2 citations
,
January 2013 in “Yearbook of Urology” Finasteride may help treat recurrent priapism in children, but more research is needed.
1 citations
,
August 2020 in “REMUS - Revista Estudiantil de Medicina de la Universidad de Sonora” Erectile dysfunction is linked to marital issues in patients with benign prostatic hyperplasia.
January 2020 in “Fertility and Sterility” The conclusion is that it's currently unclear if certain rare medical conditions are caused by specific factors due to mostly observational data.
August 2023 in “International journal of impotence research” Many dermatologists believe finasteride can cause sexual side effects and counsel patients about them.
6 citations
,
September 2016 in “Journal of Mind and Medical Sciences” Finasteride can cause side effects, some lasting after treatment ends, and may lead to severe depression or suicidal thoughts.
100 citations
,
July 2004 in “The Journal of Sexual Medicine” Hormones like estrogen, testosterone, progesterone, and prolactin play complex roles in female sexual function, with testosterone potentially improving sexual desire, arousal, and satisfaction. However, more research is needed to establish safe and effective hormone treatments for female sexual dysfunction.
5-Alpha reductase inhibitors help treat enlarged prostate but may cause sexual side effects.
90 citations
,
December 2007 in “Current Oncology” Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.
December 2016 in “The Journal of Sexual Medicine” Finasteride for hair loss may cause erectile dysfunction due to tissue fibrosis, and various factors contribute to female sexual dysfunction.
May 2015 in “Journal of The American Academy of Dermatology” Young men taking finasteride for hair loss have a higher risk of sexual dysfunction.
January 2010 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Finasteride may be a promising treatment for recurrent priapism in sickle cell anemia.
1 citations
,
January 2010 in “Endocrine abstracts”
24 citations
,
March 2017 in “Journal of The European Academy of Dermatology and Venereology” Finasteride use linked to increased risk of sexual dysfunction, especially in younger people.
177 citations
,
July 2004 in “The Journal of Sexual Medicine” Experts recommend thorough medical, sexual, and psychosocial assessments for women's sexual dysfunctions, and suggest individualized treatment plans with regular check-ups. They also mention potential use of estrogen and androgen therapy, but with caution due to safety concerns.
31 citations
,
September 2008 in “International Journal of Andrology” 5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.
75 citations
,
January 2014 in “Korean Journal of Urology” 5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” Current drug safety systems fail to detect long-term side effects, needing improvements to protect health and trust.
May 2022 in “The Journal of Sexual Medicine” Finasteride is linked to sexual dysfunction, especially in younger men using it for hair loss.
May 2023 in “The Journal of Sexual Medicine” Men with self-diagnosed PFS-related ED have normal erectile hemodynamics.
2 citations
,
January 2015 in “Journal of Investigative Dermatology”
73 citations
,
July 2013 in “The Journal of Sexual Medicine” Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.
1 citations
,
July 2015 in “Cambridge University Press eBooks” Testosterone therapy can improve sexual function in women but long-term safety is unclear.
8 citations
,
May 2016 in “Indian Journal of Pharmacology” Finasteride and dutasteride can cause severe, lasting side effects.
October 2007 in “Nature Clinical Practice Urology”