research Many Paths to Alopecia via Compromised Regeneration of Hair Follicle Stem Cells
Different problems with hair stem cell renewal can lead to hair loss.
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research Finasteride as a potential tool to improve Mesenchymal stem cell transplantation for myocardial infarction
Finasteride may improve stem cell therapy for heart attacks by increasing cell survival.
research 947 Accelerating wound healing mechanisms with cold atmospheric plasma
Cold atmospheric plasma may speed up wound healing and control infections.
research 943 Temporal-spatial activation of Wnt-signaling within Type1 / Type 2 immunity during wound healing
Wnt-signaling is regulated differently in skin cells and immune responses during wound healing.
research 973 Dipeptidyl-peptidase 4 (DPP4)-positive fibroblasts are responsible for secretion of pro-fibrotic matrix proteins in the human skin
DPP4-positive fibroblasts play a major role in producing proteins that lead to skin fibrosis.
research 976 Knockout of mTOR/Akt inhibitor REDD1 results in hair cycle-independent dermal adipose expansion by promoting adipocyte differentiation
Removing REDD1 in mice increases skin fat by making fat cells larger and more numerous.
research 946 Therapeutic effect of combined platelet-rich plasma strategies on morphea
Combining platelet-rich plasma injections and gel may effectively treat morphea, improving skin elasticity and reducing pain.
research 977 The wound healing of fractional photothermolysis mimicks scarless healing with minimal myofibroblast activation
Fractional photothermolysis helps wounds heal with minimal scarring.
research 975 Antifibrogenic activities of novel vitamin D3 analogs are dependent on VDR expression in human fibroblasts
New vitamin D3 forms need the vitamin D receptor to reduce fibrosis in human cells.
research 972 The ATP-dependent chromatin remodeler BRG1 controls epidermal keratinocytes migration during human cutaneous wound healing
BRG1 is essential for skin cells to move and heal wounds properly.
research Valentina Greco: Got hair?
Valentina Greco's research shows that the environment around hair follicle stem cells is more crucial for regeneration than the stem cells themselves.
research Regenerative Biology and Medicine
The book explains the science of tissue repair and regeneration, its medical uses, challenges, and ethical concerns.
research Organogenesis From Dissociated Cells: Generation of Mature Cycling Hair Follicles From Skin-Derived Cells
Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.
research Cell Cycle Regulation and Regeneration
Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.
research Mechanisms regulating skin immunity and inflammation
The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
research Shh maintains dermal papilla identity and hair morphogenesis via a Noggin–Shh regulatory loop
Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.
research Exosomes for repair, regeneration and rejuvenation
Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.
research Complex Hair Cycle Domain Patterns and Regenerative Hair Waves in Living Rodents
Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.
research Skin Adipocyte Stem Cell Self-Renewal Is Regulated by a PDGFA/AKT-Signaling Axis
PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.
research Wnt/β‐catenin pathway in tissue injury: roles in pathology and therapeutic opportunities for regeneration
The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.
research Corticosterone inhibits GAS6 to govern hair follicle stem-cell quiescence
Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.
research Stem cells in tissues, organoids, and cancers
Stem cells are crucial for tissue growth, cancer treatment, and disease modeling, but challenges remain in clinical use.
research Hair Depigmentation Is a Biological Readout for Pharmacological Inhibition of KIT in Mice and Humans
Hair color loss can indicate the effectiveness of a drug targeting the KIT protein in mice and humans.
research Prostaglandin D2 Inhibits Wound-Induced Hair Follicle Neogenesis through the Receptor, Gpr44
Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.
research Inductive Properties of Hair Follicle Cells
Hair growth can be induced by certain cells found at the base of hair follicles, and these cells may also influence hair development and regeneration.
research EdnrB Governs Regenerative Response of Melanocyte Stem Cells by Crosstalk with Wnt Signaling
EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.
research Choreographing Immunity in the Skin Epithelial Barrier
The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.
research Alopecia areata: a review on diagnosis, immunological etiopathogenesis and treatment options
The document concludes that while there are various treatments for Alopecia Areata, there is no cure, and individualized treatment plans are essential due to varying effectiveness.
research Noncoding dsRNA induces retinoic acid synthesis to stimulate hair follicle regeneration via TLR3
Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.
research Cellular senescence in tissue repair: every cloud has a silver lining
Cell aging can be both good and bad for tissue repair.