94 citations
,
June 2016 in “The FASEB Journal” The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.
71 citations
,
February 2020 in “Journal of Translational Medicine” Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.
65 citations
,
November 2012 in “Tissue Engineering Part B-reviews” Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.
64 citations
,
August 2013 in “Mayo Clinic Proceedings” Wound healing insights can improve regenerative medicine.
46 citations
,
March 2015 in “Regeneration” Mice can grow new hair follicles after skin wounds through a process not involving existing hair stem cells, but requiring more research to understand fully.
39 citations
,
April 2015 in “Regeneration” Lizards can regrow their tails, and studying this process helps understand scar-free healing and limb regeneration.
37 citations
,
February 2019 in “Experimental Dermatology” Spiny mice are better at regenerating hair after injury than laboratory mice and could help us understand how to improve human skin repair.
33 citations
,
September 2017 in “Molecules” Red ginseng oil and its components help promote hair regrowth and could treat hair loss.
30 citations
,
March 2017 in “ACS biomaterials science & engineering” Hair follicles are valuable for regenerative medicine and wound healing.
29 citations
,
December 2019 in “Stem Cells Translational Medicine” Fully regenerating human hair follicles not yet achieved.
24 citations
,
October 2017 in “Scientific reports” Changing light exposure can affect hair growth timing in goats, possibly due to a key gene, CSDC2.
23 citations
,
December 2013 in “Regenerative Medicine” Hair follicle culture helps develop new treatments for hair loss.
21 citations
,
October 2009 in “Biochemical Engineering Journal” Stem cell therapy is a promising approach for hair regrowth despite potential side effects.
17 citations
,
June 2018 in “Frontiers in Physiology” ADM scaffolds help skin heal by promoting a healing-type immune response.
17 citations
,
December 2010 in “Journal of Investigative Dermatology” Flightless I protein affects hair growth, with low levels delaying it and high levels increasing hair length in rodents.
15 citations
,
February 2021 in “Scientific Reports” A specific group of stem cells can help regenerate hair continuously.
15 citations
,
January 2019 in “Experimental Dermatology” Lanyu pigs show that partial-thickness wounds can partially regenerate important skin structures, which may help improve human skin healing.
13 citations
,
December 2014 in “Stem Cells” Hair and skin can regenerate without bulge stem cells due to other compensating cells.
11 citations
,
February 2021 in “Biomedicines” Bacteria in our hair can affect its health and growth, and studying these bacteria could help us understand hair diseases better.
11 citations
,
June 2016 in “npj Regenerative Medicine” The symposium concluded that understanding how different species repair tissue and how this changes with age can help advance regenerative medicine.
10 citations
,
September 2018 in “Regenerative Medicine” New hair can grow from large wounds in mice, but less so as they age, involving reprogramming of skin cells and specific molecular pathways.
8 citations
,
January 2015 in “Clinical and Experimental Dermatology” A new model for hair regeneration in mice was created in 2015, which is faster and less invasive than the old method, producing normal hairs in about 21 days.
7 citations
,
November 2020 in “Experimental Dermatology” Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.
6 citations
,
October 2020 in “Journal of Cellular and Molecular Medicine” 3D culture helps maintain hair growth cells better than 2D culture and identifies key genes for potential hair loss treatments.
1 citations
,
October 2013 Different ectodermal organs like hair and feathers regenerate differently, with specific stem cells and signals involved in their growth and response to the environment.
April 2026 in “Frontiers in Cell and Developmental Biology” CD200- cells in hair follicles have a higher ability to regenerate hair.
February 2026 in “International Journal of Web of Multidisciplinary Studies” Restoring microbial balance and using exosome therapies may help treat hair disorders like alopecia and acne.
Using scalp stem cells can improve hair transplants.
Elastin-like recombinamers show promise for better wound healing and skin regeneration.
November 2023 in “npj regenerative medicine” Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.