research Review on Alopecia Areata in the Middle East and Africa: Landscape and Unmet Needs
The Middle East and Africa need better data, treatment consensus, and support for Alopecia Areata.
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research Differentiation of Adipose Derived Stem Cells by Stimulating with Extracellular Vesicles Secreted from Dermal Papilla Cells Activated with Osteogenic and Adipogenic Inducers
The study investigated the differentiation of adipose-derived stem cells (ASCs) into dermal papilla cell (DPC)-like cells using extracellular vesicles (EVs) from DPCs activated with osteogenic and adipogenic inducers. The research demonstrated that the CAO1/2 medium, when supplemented with FGF2 and PDGF-AA, enhanced the expression of hair-inductive genes and maintained DPC-specific properties, leading to increased hair-forming activity. The study highlighted the role of specific microRNAs in regulating hair growth and suggested that DPC-EVs could effectively transform ASCs into cells with hair formation activity. This approach showed potential for hair regeneration therapies, offering a novel method for treating hair-related conditions like alopecia. However, the study acknowledged limitations in understanding miRNA expression and the characterization of DPC-EVs, indicating a need for further research.
research Investigating Alopecia Areata and its Connection to The High-Mobility Group Box 1: Review Article
Alopecia areata causes patchy hair loss and involves immune system disruptions.
research Visual Diagnosis: The Case of the Balding Preschooler
A 4-year-old girl with hair loss was diagnosed with early-onset trichotillomania and improved with behavioral interventions.
research Proceedings of the Ninth World Congress for Hair Research (2015)
The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.
research The pathogenesis of alopecia areata
Alopecia areata is an autoimmune disease affecting hair follicles and may harm heart health.
research Study of therapeutic comparison of tacrolimus 0.1% and minoxidil 2% in alopecia areata
Minoxidil 2% is more effective than tacrolimus 0.1% for hair regrowth in mild to moderate patchy hair loss, and combining both might give better results.
research Topical Delivery of Atraric Acid Derived from Stereocaulon japonicum with Enhanced Skin Permeation and Hair Regrowth Activity for Androgenic Alopecia
AA–TF#15 significantly promotes hair regrowth and could be an effective treatment for androgenic alopecia.
research Recent Advances in the Pathogenesis of Autoimmune Hair Loss Disease Alopecia Areata
Alopecia areata is caused by immune system attacks on hair follicles, often triggered by viral infections.
research Trichoscopy in alopecias: Diagnosis simplified
Trichoscopy is a useful, non-invasive way to diagnose different types of hair loss.
research Expression of Cyclooxygenase Isozymes During Morphogenesis and Cycling of Pelage Hair Follicles in Mouse Skin: Precocious Onset of the First Catagen Phase and Alopecia upon Cyclooxygenase-2 Overexpression
Overexpression of COX-2 causes early hair loss in mice, but can be prevented with a COX-2 inhibitor.
research Therapeutic Approach to Vaccine-Induced Ischemic Dermatopathy in a Pomeranian Dog with Refractory Alopecia
A tailored treatment improved a Pomeranian dog's skin and hair issues caused by a vaccine.
research Effects of Seasonality and Pregnancy on Hair Loss and Regrowth in Rhesus Macaques
Hair loss peaks in spring and regrowth in late summer, with pregnant females losing the most hair.
research Quantitative Analysis of Hair Luster in a Novel Ultraviolet-Irradiated Mouse Model
UV exposure reduced hair shine in mice, but minoxidil helped restore it.
research Therapeutic Evaluvation of Patients with Alopecia Areata.
Both Betasalic ointment and 5% minoxidil are effective and safe for treating Alopecia Areata.
research Laser on Hair Regrowth
Low-Level Laser Therapy might be a good alternative for hair loss when other treatments fail, but its effectiveness varies and more research is needed.
research Prognosis in patients with alopecia areata with poliosis: A retrospective cohort study of 479 cases
Poliosis is common in severe alopecia areata but doesn't significantly affect overall prognosis.
research Optimization and Transfollicular Delivery of Finasteride-Loaded Proniosomes for Hair Growth Stimulation in C57BL/6Mlac Mice
Finasteride-loaded proniosomes effectively promote hair growth in mice.
research Motivations and stake management in producing YouTube 'bro-science' videos for baldness treatment
Creators of YouTube 'bro-science' baldness videos are driven by a need to share and persuade, often emphasizing authenticity and community building, while navigating trust issues related to commercial ties.
research Exacerbation of alopecia areata: A possible complication of sodium tetradecyl sulphate foam sclerotherapy treatment for varicose veins
A woman's hair loss condition got worse after her varicose vein treatment with a specific foam.
research INVESTIGATING THE MECHANISMS UNDERLYING THE PATHOGENESIS OF ALOPECIA AREATA
Alopecia areata may be treated by using EGCG to balance immune cells and reduce inflammation.
research Androgenetic alopecia: An autosomal dominant disorder
Hair loss in androgenetic alopecia is caused by genetic factors and androgen excess, and can be treated with combined therapies.
research ‘Hirsutism’: A Psychological Analysis
Women with excess body hair feel psychological distress influenced by societal beauty standards, but distress isn't directly linked to the amount of hair.
research Diverse cellular players orchestrate regeneration after wounding
Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.
research Combined Diet and Supplementation Therapy Resolves Alopecia Areata in a Paediatric Patient: A Case Study
A child's hair loss from alopecia areata was fully reversed in five months using diet and supplements.
research Application of Ostrich Antibodies to the Restoration of Hair Growth, a Preliminary and Case Report
Ostrich antibodies helped regrow hair in men with hair loss, but the application needs to be easier.
research ALOPECIA AREATA-A CLINICAL ANALYSIS
Alopecia areata causes patchy hair loss due to unknown factors, affecting all ages and genders.
research What is Alopecia?
Alopecia is a condition causing hair loss that can impact looks and mental health.
research A comparison of vertical versus transverse sections for the histopathologic diagnosis of alopecias
Transverse sections are better for non-scarring hair loss, vertical sections are better for lichen planopilaris, and either method works for other scarring hair loss types.
research Treatments for Androgenetic Alopecia and Alopecia Areata
Minoxidil and finasteride treat hair loss; more research needed for other options.