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DNA Dioxygenases Tet2/3 Regulate Gene Promoter Accessibility and Three-Dimensional Chromatin Topology in Lineage-Specific Loci to Control Hair Growth

research 723 DNA dioxygenases Tet2/3 regulate gene promoter accessibility and three-dimensional chromatin topology in lineage-specific loci to control hair growth

July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

Tet2 and Tet3 enzymes are essential for controlling hair growth by affecting DNA demethylation and gene expression in mice.

research Update on the therapeutic role of metformin in the management of polycystic ovary syndrome: Effects on pathophysiologic process and fertility outcomes

12 citations , February 2025 in “Women s Health”

Metformin helps manage PCOS by improving fertility and is safe for pregnancy, especially when combined with certain treatments.

DNA Dioxygenases Tet2/3 Regulate Gene Promoter Accessibility and Chromatin Topology in Lineage-Specific Loci to Control Epithelial Differentiation

research DNA dioxygenases Tet2/3 regulate gene promoter accessibility and chromatin topology in lineage-specific loci to control epithelial differentiation

3 citations , January 2023 in “Science advances”

The enzymes Tet2 and Tet3 are important for skin cell development and hair growth.

research Green and Emerging Microextraction Strategies for Bioanalytical Determination of Hormones: Trends, Challenges, and Applications

November 2025 in “Molecules”

Microextraction techniques improve hormone testing while being environmentally friendly.

research Biomedical applications of organoids in genetic diseases

December 2024 in “Medical Review”

Organoids help study and treat genetic diseases, offering personalized medicine and therapy testing.

P21Waf1/Cip1 Is Differentially Expressed in Epidermal Versus Follicular Melanocytes and Melanoma Cells and Is Phenotypically Regulated by UVB-Mediated Apoptosis

research 1272 p21Waf1/Cip1 is differentially expressed in epidermal versus follicular melanocytes and melanoma cells and is phenotypically regulated by UVB-mediated apoptosis

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

The protein p21 is more abundant in normal skin cells than in melanoma cells and may help protect against melanoma, with UVB light affecting its levels.

research Alert to US physicians: DHEA, widely used as an OTC androgen supplement, may exacerbate COVID-19

7 citations , December 2020 in “Endocrine-related Cancer”

The over-the-counter supplement DHEA could make COVID-19 worse, especially in diabetics and people with G6PD deficiency.

research Sox9 expression in canine epithelial skin tumors

8 citations , July 2015 in “European journal of histochemistry”

Sox9 is present in most canine skin tumors and may help understand stem cells' role in these cancers.

research Advancing mitochondrial therapeutics: Synthesis and pharmacological evaluation of pyrazole-based inhibitors targeting the mitochondrial pyruvate carrier

4 citations , December 2024 in “European Journal of Medicinal Chemistry”

New pyrazole-based inhibitors show promise for treating metabolic diseases and other conditions.

Immunohistochemical, Pharmacovigilance, and Omics Analyses Reveal the Involvement of ATP-Sensitive K+ Channel Subunits in Cancers: Role in Drug-Disease Interactions

research Immunohistochemical, pharmacovigilance, and omics analyses reveal the involvement of ATP-sensitive K+ channel subunits in cancers: role in drug–disease interactions

3 citations , April 2023 in “Frontiers in Pharmacology”

ATP-sensitive K+ channel subunits, particularly Sur2A, play a significant role in various cancers.

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