research Drug-Induced Melasma in Patients on 5-Alpha Reductase Inhibitors: A Case Report
Finasteride can cause melasma, especially in people with darker skin.
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210-240 / 1000+ resultsresearch 08.33 Treatment of rheumatoid arthritis patients: comparative efficacy of four treatment regimens
MTX and GC combinations are the most effective for early rheumatoid arthritis.
research Inhibition of 5α-reductase in the nucleus accumbens counters sensorimotor gating deficits induced by dopaminergic activation
Finasteride may help improve certain brain function issues linked to dopamine.
research Chronic Exposure with 5‐Alpha Reductase Inhibitor Ameliorates Anxiety and Depression‐like Behaviors By Reducing Systemic Oxidative Stress in D‐galactose‐Induced Aging Male Rats
Finasteride may help reduce anxiety and depression in elderly but might cause depression in young men.
research A Review of the FAERS Data on 5-Alpha Reductase Inhibitors: Implications for Postfinasteride Syndrome
The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.
research High‐dose mizoribine treatment for adolescents with systemic lupus erythematosus
High-dose mizoribine effectively controls symptoms in adolescents with lupus while reducing steroid use, with manageable side effects.
research Depression Risk in the Treatment of Moderate to Severe Acne with Isotretinoin
No proven link between isotretinoin and depression.
research Finasteride Use Is Associated with Higher Odds of Obstructive Sleep Apnea: Results from the US Food and Drug Administration Adverse Events Reporting System.
Finasteride use is linked to a higher risk of obstructive sleep apnea.
research Post-SSRI sexual dysfunction & other enduring sexual dysfunctions
SSRI antidepressants can cause long-lasting sexual problems.
research Anxiety-, and Depression-like Behaviour Following Short-Term Finasteride Administration is Associated with Impaired Synaptic Plasticity and Cognitive Behaviour in Male Rats
Short-term finasteride use in male rats caused anxiety, depression, and memory problems.
research High Real-World Medication Adherence and Durable Clinical Benefit in Medicare Patients Treated with 5-Alpha Reductase Inhibitors for Benign Prostatic Hyperplasia
Older patients sticking to their prostate medication saw lasting health benefits.
research Depressive symptoms and suicidal thoughts among former users of finasteride with persistent sexual side effects
research Testosterone Therapy in Premenopausal Women
Testosterone therapy may improve mood, well-being, and sexual function in premenopausal women, but more research is needed on its long-term safety and effectiveness.
research Failing Public Health Again? Analytical Review of Depression and Suicidality From Finasteride
Finasteride may increase depression and suicide risks, needing better safety checks and informed consent.
research Progesterone Promotes Anti-Anxiety/Depressant-like Behavior and Trophic Actions of BDNF in the Hippocampus of Female Nuclear Progesterone Receptor, but Not 5α-Reductase, Knockout Mice
Progesterone reduces anxiety and depression in female mice by increasing BDNF in the brain, needing 5α-reduction and estradiol.
research Clinical comparison of extended-release divalproex versus delayed-release divalproex: pooled data analyses from nine trials
Extended-release divalproex is better tolerated and more effective for seizures and psychiatric symptoms than delayed-release divalproex, but doesn't reduce hair loss.
research Supplementary Material for: Drug-Induced Melasma in Patients on 5-Alpha Reductase Inhibitors: A Case Report
Finasteride can cause melasma, especially in people with darker skin.
research 5α-Reductase Isoenzymes: From Neurosteroid Biosynthesis to Neuropsychiatric Outcomes
Finasteride and dutasteride may cause depression and anxiety, especially in younger men.
research AB0597 Comparative analysis of safety data of four treatment regimens in early rheumatoid arthritis patients
Methotrexate plus prednisolone had the fewest serious side effects.
research Isotretinoin-induced gynecomastia.
Isotretinoin can cause gynecomastia by lowering testosterone levels.
research RU 58841-myristate–prodrug development for topical treatment of acne and androgenetic alopecia.
RUM-loaded SLN shows promise for treating acne and hair loss topically.
research The Comparative Effects Between Long‐Term and Short‐Term Treatment of Finasteride on Anxiety‐Like and Depression‐Like Behaviors in Early Senescent Male Rats
Long-term Finasteride treatment reduces depression better than short-term treatment in rats.
research Attenuation of 5α-reductase-mediated progesterone metabolism promotes differentiation of human endometrial stromal cells for the establishment of pregnancy
Reducing 5α-reductase activity helps endometrial cells differentiate, aiding pregnancy.
research The Biomolecular Effects of Finasteride on Male Rat Brain during Administration and after Discontinuation
Finasteride temporarily suppresses brain activity, but some effects last even after stopping.
research Cognitive and mood side effects of lower urinary tract medication
Some medications for bladder problems can cause memory issues or mood changes, and doctors should monitor these side effects.
research A prospective trial of the effects of isotretinoin on quality of life and depressive symptoms
Acne treatment, including isotretinoin, improves quality of life and does not worsen depression.
research Unconventional side effects of antidepressants: Focus on emotional blunting
Some antidepressants can cause emotional numbness and other unusual side effects.
research Decision letter for "The Comparative Effects Between Long‐Term and Short‐Term Treatment of Finasteride on Anxiety‐Like and Depression‐Like Behaviors in Early Senescent Male Rats"
research Decision letter for "The Comparative Effects Between Long‐Term and Short‐Term Treatment of Finasteride on Anxiety‐Like and Depression‐Like Behaviors in Early Senescent Male Rats"
research Systematic review: depression, suicidal ideation with finasteride
Finasteride increases risk of depression, possibly suicidal thoughts, and sexual dysfunction.