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Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.

Drug repurposing is a faster, cheaper way to develop new treatments using existing drugs.

Some treatments work for common baldness, but there's less evidence for other hair loss types, and more research is needed.

Smoking can cause yellow discoloration of upper lip hair and nails.

Old drugs like finasteride and spironolactone are being successfully used for hair loss and skin conditions, and many other drugs show promise for new uses in dermatology.

A rash from semaglutide may be due to propylene glycol, not the drug itself.

Zinc supplements effectively treat inherited zinc deficiency in infants.

Magnetized saline water hydrogel helps heal pressure ulcers quickly in elderly patients.

Massive minoxidil ingestion can cause prolonged shock requiring extended supportive care.

Benign ovarian tumors can cause excess male hormones and related conditions in postmenopausal women.

Donor lymphocyte infusions effectively treated leukemia relapse but caused vitiligo and alopecia areata.

Nails can reveal important health information about skin and body conditions.

A young Saudi girl with uncontrolled type 1 diabetes and hypothyroidism had two rare conditions, Mauriac syndrome and Van Wyk–Grumbach syndrome.

Excessive eyelash growth from erlotinib may indicate positive tumor response and help treat madarosis.

Skin tags may be linked to metabolic syndrome.

Hormonal therapy is a treatment option for acne, the only medical treatment for hirsutism, and the most promising for androgenetic alopecia.

Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.

GLP-1 agonists may help treat certain skin conditions.

Adaptive coping reduces PCOS symptoms, while maladaptive coping worsens them.

Hyperprolactinemia should be treated before confirming a PCOS diagnosis.

Eating disorders are serious, often undiagnosed conditions requiring early treatment, with anorexia being the most deadly and binge-eating the most treatable.

HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.

Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.