research Normal Pubertal Development: Part I: The Endocrine Basis of Puberty
Puberty is driven by hormonal changes, mainly influenced by genetics, nutrition, and body fat.
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research Safety concerns regarding 5α reductase inhibitors for the treatment of androgenetic alopecia
5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.
research Gender-Affirming Hormone Therapy for Transgender Men
Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.
research Managing Polycystic Ovary Syndrome: A Cognitive Behavioral Strategy
Cognitive behavioral strategies help women with PCOS make lifestyle changes to improve their health.
research A computational approach to mechanistic and predictive toxicology of pesticides
Pesticides can cause reproductive and adrenal health issues.
research Cross-species sensitivity to a novel androgen receptor agonist of potential environmental concern, spironolactone
Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.
research Final Report on the Safety Assessment of Hypericum Perforatum Extract and Hypericum Perforatum Oil
St. John's Wort extract and oil safety in cosmetics is unclear; more data needed on photosensitization, toxicity, and human irritation.
research Is polycystic ovary syndrome a sexual conflict? A review
The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.
research Hypothalamic DNA methylation in rats with dihydrotestosterone‐induced polycystic ovary syndrome: effects of low‐frequency electro‐acupuncture
Electro-acupuncture may help treat PCOS in rats by changing brain DNA methylation.
research Medical Options for Care of Gender Diverse and Transgender Youth
Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.
research Prevalence and characteristics of polycystic ovary syndrome in Brazilian women: protocol for a nation-wide case–control study
PCOS is common in Brazilian women and linked to metabolic and reproductive issues.
research Age, Health and Attractiveness Perception of Virtual (Rendered) Human Hair
Hair style affects perceptions of age, health, and attractiveness more than hair color does.
research Integrated Model of Care for Polycystic Ovary Syndrome
The document concludes that women with PCOS need a comprehensive care model that covers reproductive, metabolic, and psychological health to improve their quality of life.
research Nitric Oxide: Physiological Functions, Delivery, and Biomedical Applications
Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.
research Prevalence of polycystic ovary syndrome among fertile and infertile women in Minia Governorate, Egypt
Polycystic ovary syndrome (PCOS) is a major health issue for women in Egypt, affecting 14% of fertile women and 37.5% of infertile women.
research Hospital-based prevalence of polycystic ovarian syndrome among Omani women
About 7% of Omani women visiting a gynecology clinic had polycystic ovarian syndrome, similar to rates in other countries.
research Age-specific cut-off levels of anti-Müllerian hormone can be used as diagnostic markers for polycystic ovary syndrome
Different levels of anti-Müllerian hormone can help diagnose polycystic ovary syndrome in women of different ages.
research MAINTENANCE AND RESTORATION OF GROWTH IN THYROIDECTOMIZED RATS
Thyroid hormone treatments help thyroidectomized rats grow normally.
research Transcriptomic profiling in Silurana tropicalis testes exposed to finasteride
Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.
research The value of the free androgen index depends on the phenotype of polycystic ovary syndrome — a single-centre experience
The free androgen index varies among women with different types of PCOS.
research The role of metformin in the management of polycystic ovary syndrome
Metformin helps improve symptoms and reproductive outcomes in people with polycystic ovary syndrome.
research Polycystic ovary syndrome and mental health: a call to action
PCOS significantly affects women's mental health, and more research is needed to develop effective treatments for these issues.
research Impacts of Anabolic-androgenic steroid supplementation on female health and offspring: Mechanisms, side effects, and medical perspectives
Anabolic-androgenic steroids can harm women's health and their offspring.
research Non-clinical safety evaluation and risk assessment to human of aleglitazar, a dual PPAR α/γ agonist, and its major human metabolite
Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.
research Hyperandrogenism in Women: Polycystic Ovary Syndrome
The document concludes that more research is needed to create suitable diagnostic criteria and understand PCOS in Korean women, and genetics may allow for personalized treatment.
research Creating a Survey Instrument for Self-Assessed Menstrual Cycle Characteristics and Androgen Excess
In 2020, a new online survey was made to help identify Polycystic ovary syndrome (PCOS) in women, but it needs some improvements for better understanding and accuracy.
research IMPACT OF MERCURY ON SEX HORMONES (LITERATURE REVIEW)
Mercury can disrupt sex hormones and cause reproductive issues.
research GEOGRAPHICAL DIFFERENCES IN DEMOGRAPHICS AND FERTILITY HISTORIES OF MEN PRESENTING FOR INFERTILITY EVALUATION BETWEEN THE UNITED STATES AND CANADA: RESULTS FROM THE ANDROLOGY RESEARCH CONSORTIUM
American men seeking infertility evaluation are generally older, more obese, have longer infertility duration, and different lifestyle habits compared to Canadian men.
research SAFETY AND TOLERABILITY OF ANTIEPILEPTIC DRUGS AT WOMEN WITH EPILEPSY (DATA OF SVT. LUKA’S INSTITUTE OF CHILD NEUROLOGY AND EPILEPSY)
Antiepileptic drugs can cause side effects like menstrual problems and infertility in women with epilepsy, but most pregnancies result in healthy babies, with newer drugs being safer.
research Acupuncture in Polycystic Ovary Syndrome: Potential and Challenge
Acupuncture may improve reproductive and metabolic functions in PCOS without negative side effects, but more research is needed to confirm its effectiveness.