16 citations
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July 2008 in “BMC Genomics” Alpha 6 + /MHCI - cells have stem cell traits and are similar to mouse hair follicle stem cells.
January 2006 in “Zhongguo bingli shengli zazhi” Murine epidermal stem cells can develop into skin structures without rejection when implanted.
156 citations
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October 2012 in “Seminars in Cell & Developmental Biology” Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.
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August 2013 in “Stem Cells and Development” The method increases stem-like cells for better skin regeneration.
44 citations
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July 2016 in “Stem Cells Translational Medicine” Scientists discovered that certain stem cells from mice and humans can be used to grow new hair follicles and skin glands when treated with a special mixture.
February 2026 in “Frontiers in Medical Technology” Keratinocyte stem cells are crucial for skin renewal and have potential in wound healing and tissue regeneration.
1 citations
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June 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Reprogramming 3D environments can create hair follicles in the lab.
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June 1993 in “Archives of Dermatological Research” Human hair follicles can be used to create skin-like tissue for wound healing and drug testing.
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January 1989 Researchers developed a method to grow skin-like tissue from hair cells.
Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.
Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.
1 citations
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November 2023 in “Journal of Microbiology and Biotechnology” Immortalized human dermal papilla cells were created that grow better and can still help form hair.
7 citations
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January 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Skin cells control immune cell placement, helping the skin respond better to challenges.
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January 2015 in “International journal for parasitology/International Journal for Parasitology” Epidermal keratinocytes start wound healing and inflammation after schistosome infection.
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January 2019 in “International Immunology” Immune cells help keep skin healthy and repair it, but imbalance can cause disease.
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December 2001 in “Journal of Investigative Dermatology” Overexpressing ornithine decarboxylase and v-Ha-ras in keratinocytes leads to invasiveness and malignancy.
November 2022 in “Journal of Investigative Dermatology” Human-induced stem cell-created skin models can help understand skin diseases by studying the skin's layers.
44 citations
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January 2018 in “The International Journal of Developmental Biology” Stem cells in the skin help with healing and can also lead to cancer.
70 citations
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August 2006 in “Cancer Research” AP-1 controls tumor cell type by affecting key signaling pathways.
143 citations
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May 2017 in “Nature cell biology” Wounded skin cells can revert to stem cells and help heal.
19 citations
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October 2007 in “Wound Repair and Regeneration” Epidermal stem cells maintain skin health through specific niches and signaling pathways.
January 2014 in “Genes and Cells” Genetically modified cells improved skin wound healing in rats.
January 2010 in “Zhongguo xiandai yixue/Zhongguo xiandai yixue zazhi” Skin stem cells can become different cell types, like hair or bone cells, in lab conditions.
71 citations
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January 2020 in “Stem Cells International” Epidermal stem cells help heal skin, but how they work is still unclear.
28 citations
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January 2013 in “Stem cells” Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.
34 citations
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August 2016 in “Scientific Reports” Blocking TGFβ-RI signaling enhances surface ectoderm differentiation from human stem cells.
May 2020 in “Research Square (Research Square)” Human stem cells can turn into functional eye cells that might help treat retinal diseases.
January 2003 in “Zhonghua shaoshang zazhi” Murine fetal epidermal stem cells can help regenerate hair follicles.
315 citations
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June 2001 in “Nature Genetics”
April 2023 in “Journal of Investigative Dermatology” Ectomesenchyme is a key source of skin stem cells.