research PROTACs: A novel strategy for cancer drug discovery and development
PROTAC technology shows promise for cancer treatment but needs more effective E3 ligase recruiters.
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research Cell Cycle Regulation and Regeneration
Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.
research Abstract 21: Preoperative Versus Postoperative Language Specialization in Infants with Sagittal Craniosynostosis: An ERP Study
Surgery may help infants with sagittal craniosynostosis develop more typical language processing.
research Long-term live imaging, cell identification and cell tracking in regenerating crustacean legs
A new method allows detailed, continuous imaging of crustacean leg regeneration without harming the cells.
research Anticonvulsant Activity of Progesterone and Neurosteroids in Progesterone Receptor Knockout Mice
Progesterone's seizure-reducing effects are mainly due to allopregnanolone, not progesterone receptors.
research Humane rapid tranquillization of an agitated patient with an implantable cardioverter defibrillator
Non-drug methods effectively managed agitation in a patient with a heart device, leading to improved mental function.
research Commentary on Robotically Assisted Recipient Site Preparation in Hair Restoration Surgery
Robotic technology can help prepare the area for hair transplant surgery.
research Efficient In Vivo Targeting of Epidermal Stem Cells by Early Gestational Intraamniotic Injection of Lentiviral Vector Driven by the Keratin 5 Promoter
Injecting lentiviral vectors into early gestation mice effectively targets skin stem cells for potential gene therapy.
research 650 Controlling mTORC1 activity as a novel therapeutic strategy for managing human hair growth and pigmentation
Blocking mTORC1 activity with rapamycin could help increase hair pigmentation and growth, potentially reversing gray hair.
research Plasticity of differentiated cells in wound repair and tumorigenesis, part II: skin and intestine
Mature cells can re-enter the cell cycle and potentially lead to cancer.
research Knowledge Mapping of Drug Repositioning’s Theme and Development
Drug repositioning can save time and money but needs more support.
research 63748 Combined Regenerative Technique: A New Therapeutical Option for Androgenetic Alopecia
research Impaired Lef1 activation accelerates iPSC-derived keratinocytes differentiation in Hutchinson-Gilford Progeria Syndrome
Impaired LEF1 activation speeds up skin cell development in Hutchinson-Gilford Progeria Syndrome.
research Synthetically programmed antioxidant delivery by a domesticated skin commensal
Engineered bacteria can deliver antioxidants to protect skin.
research Activator Protein-1 Activity Regulates Epithelial Tumor Cell Identity
AP-1 controls tumor cell type by affecting key signaling pathways.
research Robotic surgical systems in plastic and reconstructive surgery
Robotic surgical systems are being used more in plastic and reconstructive surgery due to their precision and control, improving patient outcomes and satisfaction, despite challenges like high costs.
research Redefining hormone resistance in prostate cancer
The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.
research The Rise of Induced Pluripotent Stem Cell Approach to Hair Restoration: Correction
research Ablative Laser Resurfacing (CO2)
Ablative CO2 laser resurfacing tightens skin by destroying and regenerating skin layers.
research Small Molecule Treatments Improve Differentiation Potential of Human Amniotic Fluid Stem Cells
Small molecule treatments improve the ability of human amniotic fluid stem cells to become different cell types.
research Faculty Opinions recommendation of Fully functional hair follicle regeneration through the rearrangement of stem cells and their niches.
Scientists successfully created fully functional hair follicles using bioengineering methods and stem cells.
research Transcriptomic analysis of human skin wound healing and rejuvenation following ablative fractional laser treatment
Ablative fractional laser treatment rejuvenates skin by altering gene expression and promoting wound healing and tissue regeneration.
research Robotic Horizons in Plastic Surgery: A Look Toward the Future
Robotic technology in plastic surgery shows promise but needs more research and cost reduction for wider use.
research A preview of selected articles
The document concludes that DNA methylation and the mTOR pathway are important for stem cell function and could impact disease treatment.
research Recessive Epidermolysis Bullosa Simplex Phenotype Reproduced in Vitro
Fibroblasts from healthy donors can prevent changes seen in recessive epidermolysis bullosa simplex.
research Electrical stimulation to human dermal papilla cells for hair regenerative medicine
Electric stimulation can increase hair growth by activating certain genes in skin cells.
research Insight into Recent Advances in Degrading Androgen Receptor for Castration-Resistant Prostate Cancer
New treatments targeting androgen receptors show promise for drug-resistant prostate cancer.
research Revision Surgical Hair Restoration: Repair of Undesirable Results
Unsatisfactory hair restoration results can be significantly improved with strategic hair redistribution and new donor hair placement, despite previous surgery challenges.
research Molecular studies of Hutchinson-Gilford progeria syndrome
Suppressing the HGPS mutation may improve symptoms and suggest reversibility.
research Stem Cells and Their Niches
Understanding stem cell interactions with their environments is key for advancing regenerative medicine.