4 citations
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November 2022 in “Frontiers in Immunology” Lung and liver macrophages protect our tissues and their dysfunction can cause various diseases.
2 citations
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June 2024 in “Frontiers in Immunology” 3D cultures can create active macrophages from fat tissue.
November 2025 in “Wound Repair and Regeneration” Single-cell sequencing shows that different types of macrophages have unique roles in wound healing.
December 2013 in “Research Portal (King's College London)” Hair loss in Lichen Planopilaris is caused by immune system issues damaging hair follicles and stem cells.
306 citations
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April 2019 in “International Journal of Molecular Sciences” The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
18 citations
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November 2020 in “Frontiers in Cell and Developmental Biology” Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.
June 2024 in “Research Square (Research Square)” Jagged-1 in skin Tregs is crucial for timely wound healing by recruiting specific immune cells.
188 citations
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March 2018 in “Frontiers in Immunology” Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.
August 2017 in “Journal of Investigative Dermatology” Activin increases skin tumor formation, skin Tregs help hair growth, lymph-node removal doesn't improve melanoma survival, cells can revert to stem cells in wound healing, and skin bacteria produce peptides that may treat infections.
175 citations
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December 2014 in “PLoS Biology” Macrophages help activate hair follicle stem cells, affecting hair growth and skin repair.
September 2022 in “Research Square (Research Square)” Macrophages help maintain mammary stem cells and balance through specific signaling.
July 2024 in “Journal of Investigative Dermatology” Reactive lipids from aging cells change the extracellular matrix, affecting cell function and inflammation.
41 citations
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July 2019 in “Clinical Cosmetic and Investigational Dermatology” The skin's immune system helps it regenerate and fight infections.
September 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” Hair loss in males and females is influenced by immune cell interactions, with potential treatments identified.
9 citations
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October 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Microglia are essential for zebrafish brain repair by controlling inflammation.
5 citations
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January 2004 Stem cells help heal skin wounds by supporting tissue repair and regeneration.
4 citations
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April 2019 in “Cell Stem Cell” Certain immune cells in the skin can stop hair from growing.
15 citations
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May 2023 in “npj Regenerative Medicine” Macrophages help maintain mammary stem cells and tissue balance through specific signaling pathways.
2 citations
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March 2021 in “Molecular Immunology” Dermal macrophages might help regrow hair.
21 citations
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March 2019 in “Experimental Dermatology” Immune cells around hair follicles help control hair growth and could be targets for treating hair disorders.
65 citations
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February 2017 in “Pflügers Archiv - European Journal of Physiology” Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.
44 citations
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January 2019 in “Journal of Translational Medicine” Macrophages are essential for successful skin growth in reconstructive surgery.
25 citations
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June 2004 in “Journal of Investigative Dermatology” Macrophage-stimulating protein helps hair grow and can start hair growth phase in mice and human hair samples.
24 citations
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May 2021 in “Nature Communications” Cavity macrophages gather on organ surfaces but don't really invade or help repair the organs after injury.
18 citations
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May 2018 in “International Journal of Molecular Sciences” Human body's immune cells are more common in the layer of fat just beneath the skin than in deeper fat layers.
13 citations
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October 2020 in “Journal of Neural Transmission” CD34-positive cells help repair and form new blood vessels in salivary glands after radiation.
163 citations
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April 2019 in “Nature Communications” Mechanical stretching of the skin can promote hair growth by activating certain immune cells.
117 citations
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March 2017 in “Nature Communications” Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.
36 citations
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April 2018 in “Journal of Investigative Dermatology” Macrophages help hair growth after injury through CX3CR1 and TGF-β1.
9 citations
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August 2021 in “Biological Chemistry” ECM-inspired wound dressings can help heal chronic wounds by controlling macrophage activity.