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Isotretinoin effectively treats severe acne but can cause various side effects, with the most serious being birth defects, requiring careful monitoring and contraception.

Retinoids or their analogs could treat skin pigmentation disorders like melasma and vitiligo.

Retinoids can help treat skin pigmentation disorders by affecting melanin production.

TRα and CRABPII genes change their activity levels during goat fetal skin development.

Mutations in the P2RY5 gene cause hereditary woolly hair.

Retinoic acid, glucocorticoids, and IGF1 increase IGFBP-3 production in human dermal papilla cells, affecting hair growth.

GPRC5D is linked to the formation of hair, nails, and certain tongue areas.

Exosomes help nerve fibers grow by affecting specific cell signaling pathways.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

Plant-derived PDRN from ginseng roots effectively heals skin and improves its barrier.

TTNPB helps turn stem cells into neural stem cells, improving depression-like behaviors in rats.

Non-coding RNA boosts retinoic acid production and signaling, aiding regeneration.

Ezh2 controls skin development by balancing signals for dermal and epidermal growth.

The new micelle formulation delivers acne treatment more effectively and safely than current gels.

Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.

A substance called poly(I:C) increases a protein called carbonic anhydrase II in skin cells, which might help with skin defense and healing.

Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.

Retinoic acid helps activate hair growth in people with common hair loss by working on a specific cell growth pathway.

Retinoic acid can either maintain stem cells or make them specialize, depending on the cell type.

Retinoic acid reduces cell damage from oxidative stress.

The right amount of retinoic acid is essential for normal hair growth and development.

Retinoic acid affects male and female muscle energy use and function differently.

Retinoic acid and DMSO improve gene delivery to mouse skin for potential hair and skin disease treatment.

9-cis-retinoic acid showed some effectiveness in treating AIDS-related Kaposi sarcoma but had significant side effects at higher doses.

Hydroxypinacolone retinoate is a potent anti-aging ingredient for skin that is more effective and less irritating than other forms of retinoids.

The synthetic retinoid EC23 thickens skin and promotes hair growth more effectively and with a lower dose than natural retinoids.

Hair follicle stem cells prevent melanocyte stem cells from differentiating by controlling retinoic acid levels.

DGAT1 enzyme is crucial for healthy skin and hair by regulating retinoid levels.

Double-stranded RNA activates a pathway that causes a skin protein to be expressed in the wrong place.

Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.