April 2018 in “Journal of Investigative Dermatology” Both Th1 and Th2 immune responses are increased in alopecia areata, with Th2 response more strongly linked to how severe the disease is.
April 2018 in “Journal of Investigative Dermatology” Activating Nrf2 helps wounds heal faster by increasing hair follicle stem cells.
April 2018 in “Journal of Investigative Dermatology” Topical tofacitinib is effective in promoting hair growth for non-scarring alopecia.
66 citations
,
January 2017 in “Acta dermato-venereologica” Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.
2 citations
,
December 2018 in “Journal of cosmetic dermatology” Higher CRBP1 levels are linked to more severe alopecia areata.
1 citations
,
January 2008 in “touchREVIEWS in Endocrinology” Generalized glucocorticoid resistance causes hormone imbalances and varied symptoms due to gene mutations.
July 2025 in “Scientific Reports” Dermal papilla cell-conditioned medium can help reduce skin aging caused by oxidative stress.
175 citations
,
April 1982 in “Journal of The American Academy of Dermatology” Isotretinoin is highly effective in treating severe acne, rosacea, and gram-negative folliculitis.
47 citations
,
September 2016 in “Reviews in endocrine and metabolic disorders” The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
13 citations
,
June 2018 in “Journal of histochemistry and cytochemistry/The journal of histochemistry and cytochemistry” Laminin-511 may contribute to psoriasis by affecting skin cell growth and survival.
September 2016 in “Journal of the Egyptian Women's Dermatologic Society (Print)” Higher RBP4 levels found in people with two types of hair loss.
September 1997 in “Journal of The European Academy of Dermatology and Venereology” New treatment improves male hair loss.
December 2015 in “Dermatologic Therapy” Zinc sulfate solution is more effective than tea lotion for treating acne rosacea.
8 citations
,
October 1989 in “International Journal of Dermatology” Cytochrome P-450 enzymes in the skin help break down various substances and could be targeted to treat skin conditions.
January 2023 in “Discovery immunology” T cells and bacteria in the gut and skin help maintain health and protect against disease.
147 citations
,
April 1994 in “Drug Safety” Some drugs can cause hair loss or increase hair growth, but these effects are usually reversible when the drug is stopped.
30 citations
,
April 1990 in “Clinical Pharmacology & Therapeutics” Tretinoin cream boosts minoxidil absorption, possibly improving hair loss treatment.
1 citations
,
March 2011 in “Informa Healthcare eBooks” Isotretinoin is a preferred treatment for severe acne, often leading to long-term improvement, but requires careful monitoring due to potential side effects.
15 citations
,
October 2006 in “Journal of the American Academy of Dermatology” Liquid nitrogen spray caused a temporary, harmless swelling under the skin in an elderly woman.
May 2020 in “JOJ Dermatology & Cosmetics” A rare skin condition usually on the face was found on a man's heel.
104 citations
,
May 2003 in “Endocrinology” Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.
60 citations
,
May 2015 in “Archives of dermatological research” PPAR agonists show promise for skin conditions but need more research before being a main treatment.
29 citations
,
July 2013 in “The Journal of Sexual Medicine” Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.
28 citations
,
July 2007 in “Development” TAF4 is important for skin cell growth and helps prevent skin cancer in mice.
19 citations
,
July 2020 in “Journal of drug delivery science and technology” Nanoemulsions with minoxidil and clove oil effectively target hair follicles for better alopecia treatment.
10 citations
,
January 2010 in “Veterinary pathology” A new mutation in the hairless gene causes hair loss and skin wrinkling in mice.
10 citations
,
January 1985 in “Elsevier eBooks” Active oxygen species might be involved in skin tumor growth, but their exact role is unclear.
8 citations
,
June 2019 in “Scientific Reports” Increased PPARGC1α relates to hair thinning in common baldness.
7 citations
,
June 2016 in “Bone Research” A Chinese family had a child with a specific gene mutation causing vitamin D-resistant rickets, but the child improved with calcium and low-dose calcitriol.
7 citations
,
August 2009 in “The Journal of Rheumatology Supplement” Retinoids and narrowband UVB phototherapy are effective for treating psoriasis and can reduce treatment time when used together.