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Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Vitamins A, B3, C, D, and E can improve skin health and immunity.

LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.

Researchers created a mouse model of a type of rickets that does not cause hair loss.

Isotretinoin improves severe acne without changing androgen or insulin levels but may increase body weight and triglycerides.

Kojyl cinnamate ester derivatives can promote hair growth by increasing adiponectin production in fat tissues.

Increased PPARGC1α relates to hair thinning in common baldness.

A Chinese family had a child with a specific gene mutation causing vitamin D-resistant rickets, but the child improved with calcium and low-dose calcitriol.

TR3 is mainly found in hair follicle stem cells and may be involved in hair loss.

The RORα gene is active in different parts of cashmere goat hair follicles and may be influenced by melatonin, especially in December when hair growth changes.

Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.

Skin aging can be slowed by targeting cells, hormones, and the microbiome.

Apoptosis is essential for human skin development and forming a functional epidermis.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Different types of skin cells are organized in a special way in large wounds to help with healing and hair growth.

Skin-derived stem cells can become various cell types, including germ cell-like and oocyte-like cells.

Laminin-511 may contribute to psoriasis by affecting skin cell growth and survival.

Thyrotropin-releasing hormone may help control skin and hair growth and could aid in treating related disorders.

Epidermal stem cells have potential for personalized regenerative medicine but need careful handling to avoid cancer.

Malassezia furfur lipids improve skin health at pH 6.

Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.

Faulty inflammasome activation may lead to autoimmune skin diseases and could be a target for new treatments.

Targeting specific cell interactions may help treat skin fibrosis.

Hair follicle stem cells in hairpoor mice are disrupted, causing hair loss.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

EGFR inhibitors often cause skin problems and other side effects, but these are usually reversible and can be managed to keep patients comfortable.