research Key targets of hormonal treatment of prostate cancer. Part 2: the androgen receptor and 5α-reductase
Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.
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540-570 / 1000+ results research Merck offers money back guarantee on finasteride
Merck will refund the cost of the drug finasteride if it doesn't improve symptoms within six months or if the patient needs surgery within two years.
research Impact of Microbial Infection on Sperm Parameters of Seminal Bacteria in Asymptomatic Subfertile Males
Seminal bacteria can lower sperm quality in subfertile men.
research Re: Can Long-Term LUTS/BPH Pharmacological Treatment Alter the Outcomes of Surgical Intervention?
Long-term medication for enlarged prostate might not clearly affect the timing or outcomes of later surgery.
research External genitalia abnormalities in male rats exposed in utero to finasteride, a 5α-reductase inhibitor
Finasteride exposure in pregnancy causes genital abnormalities in male rats.
research The Distribution of Preputial Vessels in Different Severity of Rat Congenital Hypospadias Model: Imaging study using Micro-Computerized Tomograph
The junction of the inner and outer prepuce with good blood flow is best for vascular pedicle flaps.
research Erectile Dysfunction in Young Men—A Review of the Prevalence and Risk Factors
Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.
research Latent hazard in PC and BPH patients referred to antiandrogens:PC aggressiveness and NE differentiation
Long-term antiandrogen use may increase aggressive prostate cancer risk.
research Efficacy of Combination of Tamsulosin and Finasteride on Urinary Symptoms and IPSS Score for Elderly Patients with BPH
Combining tamsulosin and finasteride effectively improves urinary symptoms in elderly BPH patients.
research Finasteride and sexual side effects
Finasteride may cause sexual side effects like erectile dysfunction, but they are reversible and affect less than 2% of men.
research When two plus two must not equal four
Regulatory challenges make developing combination therapies in urology difficult and costly.
research 5alpha-reductase inhibitors/finasteride.
research Role of 5α-reductase inhibitors in benign prostatic diseases
5α-reductase inhibitors help shrink the prostate, improve urinary symptoms, and may reduce prostate cancer risk.
research Adverse Reactions to Enemas
Enemas can cause septicemia in elderly men with prostate infections.
research Terazosin reduced BPH symptoms and finasteride did not
research Hormonal manipulation of benign prostatic hyperplasia
Finasteride and dutasteride are equally effective and safe for treating benign prostatic hyperplasia.
research Apoptosis during the first wave of spermatogenesis in the testis of offspring’ rats (F1:Fin) that were born from females fertilized by males chronically treated with finasteride
research Retardation of Preputial Wound Healing in Rats with Hypospadias Induced by Flutamide
Flutamide-induced hypospadias in rats slows down early wound healing.
research Efficacy and safety of long-term administration of tamsulosin hydrochloride in patients with LUTS suggestive of BPH
Tamsulosin hydrochloride is safe and effective for long-term treatment of urinary symptoms in BPH patients.
research UP-03.20
Combination therapy with Finasteride is more effective than alpha-blocker alone for BPH symptoms in small prostate volume.
research Appropriateness of oral drugs for long-term treatment of lower urinary tract symptoms in older persons: results of a systematic literature review and international consensus validation process (LUTS-FORTA 2014)
Dutasteride, fesoterodine, and finasteride are beneficial for older patients, while most other drugs should be used cautiously or avoided.
research SUN-207 Hot Flashes, Flushing, and Sweating in a Middle-Aged Man with Pituitary Macroadenoma
Middle-aged men with unusual hot flashes should be checked for pituitary tumors.
research The Benefits of Dual Inhibition of 5α Reductase
Dutasteride reduces DHT and improves BPH symptoms more effectively than finasteride.
research Dutasteride: A Review of its Use in the Management of Prostate Disorders
Dutasteride is effective for treating prostate enlargement and reducing related surgery risk, but is not approved for preventing prostate cancer.
research Understanding the Epidemiology, Natural History, and Key Pathways Involved in Prostate Cancer
Prostate cancer was a major health issue in 2009, especially for Black men, and targeting the 5alpha-reductase enzyme could help in its prevention and treatment.
research Finasteride interferes with prostaglandin-induced CatSper signalling in human sperm
Finasteride may affect male fertility by interfering with specific sperm signaling.
research Control of testosterone 5alpha-reductase activity in the human hyperplastic prostate
Inhibiting testosterone 5alpha-reductase may help treat benign prostatic hyperplasia.
research Tamsulosin treatment for benign prostatic hyperplasia and risk of severe hypotension in men aged 40-85 years in the United States: risk window analyses using between and within patient methodology
Tamsulosin for enlarged prostate may increase the risk of severe low blood pressure, especially when starting or restarting the medication.
research Long-Term Effectiveness of Finasteride for BPH
Finasteride effectively reduces the need for surgery and urinary issues in men with BPH over the long term.
research Serenoa Repens (Saw Palmetto) for Lower Urinary Tract Symptoms (LUTS): The Evidence for Efficacy and Safety of Lipidosterolic Extracts. Part III
Saw palmetto may improve urinary symptoms with fewer sexual side effects compared to some medications.