MFN2 mutations cause mitochondrial problems, unusual fat distribution, and low leptin despite high body fat.
6 citations
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September 2015 in “Journal of Investigative Dermatology” Using special RNA to target a mutant gene fixed hair problems in mice.
April 2026 in “Human Genome Variation” The MBTPS2 gene variant c.970+5G>A is a common mutation causing IFAP syndrome.
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April 2019 in “iScience” EGFR helps control how hair grows and forms without needing p53 protein.
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January 2015 in “Sen'i Gakkaishi” Washing permed hair after using thioglycolic acid helps reform strong bonds, making hair stronger.
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August 2024 in “Aesthetic Plastic Surgery” Recipient site necrosis is a rare but serious complication of hair transplants, often linked to smoking, diabetes, and hypertension.
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January 2009 in “BMJ Case Reports” Gefitinib can cause slower, finer, brittle, and curly scalp hair.
June 2018 in “The Journal of Sexual Medicine” Finasteride helps female-pattern hair loss.
22 citations
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October 2018 in “Molecular Medicine Reports” Classic PDRN improves wound healing quality by enhancing cell migration.
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February 2002 in “Journal of Radiological Protection” Caffeine reduces radiation skin damage but doesn't affect tumor treatment.
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June 2016 in “Journal of receptor and signal transduction research” Minoxidil increases calcium levels and kills prostate cancer cells independently of calcium.
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March 2022 in “Journal of biological chemistry/The Journal of biological chemistry” Removing a specific gene in certain skin cells causes hair loss in mice by disrupting hair follicle development.
59 citations
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September 2007 in “Biochemical and Biophysical Research Communications” The TRPV3 gene mutation affects hair growth by keeping mice in the growth phase longer, which could help treat hair loss.
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August 2015 in “Journal of Experimental & Clinical Cancer Research” The photolyase-based device significantly changed the size and heat of potential skin cancer areas in patients.
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October 2021 in “Cellular & Molecular Biology Letters” New biomarkers and potential treatments for skin diseases were identified.
June 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Lef1 helps adult skin cells maintain their ability to heal wounds and regenerate hair, but the study's methods and conclusions have been questioned.
44 citations
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April 2006 in “Expert opinion on drug safety” Gefitinib can cause skin problems, diarrhea, and nausea, but rarely causes severe lung disease or hair loss.
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August 2013 in “Chinese Medical Journal” A specific gene mutation in KRT86 is linked to hair disorder in a Chinese Han family.
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May 2022 in “Genes & Diseases” 34 citations
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May 2001 in “Endocrinology” Mrp3 helps in wound healing and hair growth.
April 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” CTCF protein is essential for skin and hair follicle development in mice.
September 2024 in “Heliyon” Repeated hair dyeing significantly damages hair.
Vitamin D receptor actions without binding are crucial for healthy skin and hair.
7 citations
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January 2023 in “Anti-Cancer Drugs” Early diagnosis and treatment of EGFR inhibitor-induced folliculitis decalvans can prevent permanent hair loss.
12 citations
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July 2015 in “Experimental Dermatology” Gasdermin A3 overexpression in skin causes inflammation and hair loss.
February 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” Tandem repeats significantly influence hair color, especially darker shades, across different ancestries.
252 citations
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November 1995 in “The EMBO Journal” Blocking EGFR in mice causes hair loss and skin changes.
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August 2020 in “Current topics in medicinal chemistry” New cancer treatments aim to reduce side effects and improve effectiveness.
A protein called sFRP4 can partly inhibit hair growth.
July 2022 in “Journal of Investigative Dermatology”