5 citations
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March 2019 in “Experimental dermatology” Activating TLR3 may help produce retinoic acid, important for tissue regeneration.
18 citations
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August 2015 in “Biochemical and Biophysical Research Communications” XEDAR triggers a specific signaling pathway in cells.
303 citations
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October 2000 in “Nature” RXRα is crucial for hair growth and skin cell function.
10 citations
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June 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” Vitamin D receptor helps protect skin cells from UV damage and supports their growth.
January 2026 in “American Journal of Medical Genetics Part A” A new genetic variant causes trichothiodystrophy in two brothers, but their mother may carry it without showing symptoms.
November 2025 in “Journal of Investigative Dermatology” A new genetic mutation causing Xeroderma Pigmentosum was found in an 8-year-old girl, affecting her DNA repair.
1 citations
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September 2016 in “Journal of Dermatological Science” FGF18 treatment during hair's resting phase can protect against hair loss from radiation.
11 citations
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November 2015 in “Carcinogenesis” Deleting TNFα gene reduces skin cancer risk in certain mice.
107 citations
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March 2014 in “BoneKEy Reports” Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.
119 citations
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November 2014 in “Trends in Cell Biology” Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.
February 2025 in “Journal of Clinical Investigation” RNase L hinders hair growth by altering immune signals.
50 citations
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September 2009 in “Molecular Genetics and Metabolism” A new gene mutation causes vitamin D resistance and rickets, treatable with calcium therapy.
29 citations
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January 2010 in “Methods in Enzymology” The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.
10 citations
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September 2015 in “PLoS ONE” New mutations in the VDR gene cause vitamin D-resistant rickets without hair loss.
1 citations
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September 2025 in “Frontiers in Immunology” Folate receptor β helps suppress the immune system in macrophages and affects cancer growth and hair health.
December 2009 in “Expert review of dermatology” Vitamin D may help protect against nonmelanoma skin cancer.
July 2020 in “DOAJ (DOAJ: Directory of Open Access Journals)” Excessive sun protection might contribute to frontal fibrosing alopecia.
71 citations
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February 2012 in “The American Journal of Human Genetics” A specific ATR gene mutation is linked to a hereditary oropharyngeal cancer syndrome.
Activating certain hair follicle cells could prevent hair loss from cancer treatments.
1 citations
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January 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Injury boosts normal skin cell growth, reducing cancer cell advantage.
5 citations
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November 2015 in “International Journal of Radiation Biology” Gamma-ray exposure can cause long-lasting damage to hair follicles, affecting hair structure and color.
19 citations
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December 2015 in “Journal of Investigative Dermatology” The protein p53 directly reduces the production of Keratin 17, a skin and hair protein, in rats with radiation dermatitis.
44 citations
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October 2017 in “Scientific Reports” Far-infrared radiation improves stem cell growth and movement, helping heart therapy.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Higher SPF sunscreens provide more DNA protection, and the form of sunscreen doesn't affect protection level.
138 citations
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January 2004 in “AIDS” Some HIV treatments can harm mitochondria, potentially causing side effects like lactic acidosis and nerve damage.
53 citations
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January 2009 in “Journal of Investigative Dermatology” UVB radiation harms hair growth and health, causing cell death and other changes in human hair follicles.
8 citations
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March 2011 in “Endocrine” A new gene mutation causes vitamin D-resistant rickets and hair loss in two siblings.
37 citations
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April 2010 in “FEBS Letters” The study concludes that the EDA2R gene is activated by p53 during chemotherapy but is not necessary for chemotherapy-induced hair loss.
10 citations
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March 2016 in “Toxicology and applied pharmacology” Using A132 hair dye with sunlight can cause skin damage and hair loss.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Different types of human skin cells respond uniquely to various colors and doses of light, which could lead to specialized light treatments for skin conditions.