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Introducing the OTC gene improved symptoms in mice with OTC deficiency.
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Baricitinib showed mixed results in treating alopecia areata in children, with some improvement but also side effects.
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Baricitinib therapy helped many patients with severe alopecia regrow hair after 52 weeks.
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June 2018 in “The journal of immunology/The Journal of immunology” AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.
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