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September 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” MicroRNA-148a is crucial for maintaining healthy skin and hair growth by affecting stem cell functions.
Polygonum multiflorum, especially emodin, may help treat hair loss by targeting specific proteins, offering a new approach beyond traditional therapies.
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June 2023 in “Cells” Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
April 2026 in “International Journal of Molecular Sciences” Targeting non-Smad pathways in TGF-β signaling may improve keloid treatment.
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October 2017 in “Stem cells” Wnt signaling is crucial for skin development and hair growth.
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February 2019 in “International Journal of Molecular Sciences” Activin B can boost hair growth by promoting cell proliferation and cell cycle progression.
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September 2024 in “Journal of Clinical Medicine” Hidradenitis suppurativa is linked to autoinflammation and immune system issues.
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August 2024 in “Frontiers in Pharmacology” Natural products may be safer and effective alternatives for managing heart attacks.
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August 2025 in “Journal of Translational Medicine” CD44 signaling can help heal wounds without scars.
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May 2021 in “EMBO journal” Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.
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September 2025 in “Biomolecules” The effect of GLP-1 RAs on erectile function is unclear and needs more research.
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June 2024 in “Skin Research and Technology” Human dermal fibroblast proteins help restore nerves during healing.
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January 2023 in “Signal Transduction and Targeted Therapy” New therapies are being developed that target integrin pathways to treat various diseases.
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November 2021 in “Annual review of pathology” Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.
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November 2021 in “International Journal of Molecular Sciences” Mutant keratins cause inflammation in Epidermolysis Bullosa Simplex, suggesting targeting them could help treat the disorder.
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October 2021 in “Frontiers in Physiology” Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.
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May 2022 in “Frontiers in Immunology” Reprogramming macrophages to resolve inflammation can help reduce severe COVID-19 complications.
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September 2024 in “Molecules” Turmeric essential oil compounds have potential as safe, effective drugs.
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February 2018 in “Oncotarget” Lower SMAD2/3 activation predicts more severe skin cancer.
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December 2022 in “Cells” Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.
February 2026 in “International Journal of Molecular Sciences” Extracellular vesicles show promise for medical use but face challenges in standardization and safety.
September 2025 in “PubMed” Mechanical stimulation and new therapies show promise for hair regrowth.
Curcuma aeruginosa Roxb. may help treat hair loss by affecting specific biological pathways.
June 2024 in “Computational and Structural Biotechnology Journal” Multi-omics techniques help understand the molecular causes of androgenetic alopecia.
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August 2011 in “The EMBO Journal” The enzyme PA-PLA1α is important for proper hair follicle development.
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October 2022 in “Springer eBooks” Testosterone is key for male sexual function, and treating hormone imbalances can improve sexual issues.
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November 2005 in “Journal of Andrology” The meeting highlighted promising genetic treatments for male fertility issues but noted concerns about certain cancer risks and ICSI safety.
March 2025 in “Advanced Science” Bioengineered hair germs using special hydrogels can help regenerate hair follicles and treat hair loss.
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January 2024 in “Fibrosis” Hydrogels show promise for scarless wound healing by reducing skin fibrosis.
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June 2014 in “Journal of developmental biology” Retinoic acid helps change skin cells and is important for skin development and hair growth.