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Methotrexate is effective for rheumatoid arthritis but can cause side effects.

The new synthetic retinoid RO 13-6298 effectively treated severe psoriasis at low doses with manageable side effects.

R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.

Ritlecitinib may cause serious side effects like blood clots in alopecia areata patients.

A man had a severe allergic reaction to sulfasalazine, with symptoms improving after treatment and follow-up.

5α-reductase inhibitors may prevent prostate cancer but could also raise the risk of more severe cancers.

5-Alpha reductase inhibitors are safe long-term but may be outdated for preventing less significant prostate cancer.

Using 5-alpha reductase inhibitors may lower the risk of breast cancer in females.

Taking 5-alpha reductase inhibitors does not increase breast cancer risk in men.

5α-reductase inhibitors lower overall prostate cancer risk but not high-grade cancer risk; longer-term screening and new treatments show promise.

Sonidegib and vismodegib have different side effects and reporting patterns.

5α-reductase inhibitors may help with prostate cancer but could increase the risk of severe tumors, so careful use is advised.

5-ARI therapy may help prevent prostate cancer progression.

5-alpha-reductase inhibitors can lower prostate cancer risk but may increase high-grade tumors and cause sexual side effects.

Using hair loss drugs finasteride and dutasteride may cause sexual side effects.

Taking spironolactone and linestrenol for androgen excess can lead to lower bone density in young women.

SMR-2 and SMR-6 are much more toxic than retinoic acid, causing severe symptoms and organ damage in mice.

Retinoic acid affects male and female muscle energy use and function differently.

Early detection and stopping the drug are key to managing DRESS, and careful monitoring is important due to possible severe reactions.

Ritlecitinib is generally safe for long-term use, with mostly mild side effects.

Two siblings stayed rickets-free for 14 years after stopping treatment.

Ritlecitinib is generally safe for alopecia areata patients over 72 months.

Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.

Child with rickets improved with a specific vitamin D therapy, but alopecia did not change.

Ritlecitinib may be more effective for severe alopecia areata than conventional treatments.

Some prostate cancers have gene changes that may affect treatment with certain drugs.

Isotretinoin is a preferred treatment for severe acne, often leading to long-term improvement, but requires careful monitoring due to potential side effects.