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The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.

Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.

The KRTAP21-1 gene affects wool yield and can help improve wool production.

TRPV4 channel affects skin health and could be a target for treating skin disorders.

Dkk4 protein helps control how hair grows and its arrangement.

The KRTAP36-1 gene affects wool quality in Chinese Tan lambs.

The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.

PRX01, PRX44, and PRX73 affect root hair growth by interacting with extensins in Arabidopsis.

Keratin K14 expression varies between hair follicles and epidermis, affecting cell differentiation.

STIM1 is essential for sweat secretion.

A new gene mutation causes vitamin D resistance and rickets, treatable with calcium therapy.

c-Myc, Max, and Bin1 help hair follicle cells mature and die.

Blocking certain receptors in the lungs might help treat a specific type of asthma.

A mutation in the KRT74 gene causes tightly curled hair.

MC1R gene variations affect skin, hair color, UV sensitivity, and melanoma risk.

DS-2325a is safe and well-tolerated, supporting further development for Netherton Syndrome treatment.

Different keratins in hair follicles can help identify hair tumor origins.

A new mutation in the TRPS1 gene was found in a Ukrainian girl with Trichorhinophalangeal syndrome type I.

BMAL1 controls skin cell growth and UV damage risk, peaking at night.

Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.

Corin helps control salt and sweat release in sweat glands.

Stem cell behavior varies with stimuli, and lineage changes can happen without affecting stem cell division.

The 4C32 gene may help in mouse skin development and differentiation.

The gene KAP22-1 affects wool yield and fiber shape in sheep.

KLF4 is important for keeping hair follicle stem cells inactive.