research Rapunzel Syndrome: A Rare Cause of Biliary Obstruction
Trichobezoars can cause serious health issues like biliary obstruction, and treatment includes surgery and therapy to prevent recurrence.
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research Androgens and ovarian function: translation from basic discovery research to clinical impact
Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.
research Design, synthesis and anti-tumor evaluation of novel thiohydantoin congeners as androgen receptor antagonists with in vivo study.
A new compound, 3a, effectively fights prostate cancer better than finasteride.
research Two Calcium Sensor-Activated Kinases Function in Root Hair Growth
CIPK13 and CIPK18 genes are crucial for root hair growth in plants.
research Novel aldo-keto reductase 1C3 inhibitor affects androgen metabolism but not ovarian function in healthy women: a phase 1 study
The inhibitor affects androgen metabolism but not ovarian function.
research Table 1_Subcutaneous injection of genetically engineered exosomes for androgenic alopecia treatment.xlsx
EX104 effectively promotes hair growth and regenerates follicles in androgenetic alopecia.
research High‐dose mizoribine treatment for adolescents with systemic lupus erythematosus
High-dose mizoribine effectively controls symptoms in adolescents with lupus while reducing steroid use, with manageable side effects.
research Design of Liposome Formulations for CRISPR/Cas9 Enzyme Immobilization: Evaluation of 5-Alpha-Reductase Enzyme Knockout for Androgenic Disorders
New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.
research Influência da Disbiose na Patologia do Couro Cabeludo
Imbalance in scalp bacteria can affect hair and scalp health, potentially leading to conditions like hair loss, psoriasis, and dandruff.
research Indicações, eficácia e efeitos colaterais do Minoxidil oral: revisão integrativa
Oral Minoxidil effectively treats hair loss with increased hair growth as a side effect, and low doses are generally safe.
research Extraction of follicular horny impactions of the face by polymers. Efficacy and safety of a cosmetic pore-cleansing strip (Bioré)
Bioré Pore Perfect strips effectively and safely clean pores on the nose.
research New signalling molecules regulating root hair tip growth
NADPH oxidase and phospholipase D help root hairs grow by activating calcium channels.
research miR-200a Targets PITX2 to Mediate Goose Fibroblast Proliferation Through the Wnt Pathway
miR-200a reduces goose fibroblast growth by targeting PITX2 in the Wnt pathway.
research FOXE1, A New Transcriptional Target of GLI2 Is Expressed in Human Epidermis and Basal Cell Carcinoma
research Pharmacological Activation of Thermo–Transient Receptor Potential Vanilloid 3 Channels Inhibits Hair Growth by Inducing Cell Death of Hair Follicle Outer Root Sheath
Activating TRPV3 channels stops hair growth by killing hair follicle cells.
research Reversal of androgenic alopecia by minoxidil: lack of effect of simultaneously administered intermediate doses of cyproterone acetate.
Minoxidil can regrow hair, but cyproterone acetate doesn't help when used together.
research Hair regrowth boosting via minoxidil cubosomes: Formulation development, in vivo hair regrowth evaluation, histopathological examination and confocal laser microscopy imaging
A new version of minoxidil, a hair loss treatment, was made using nanotechnology. This version, called minoxidil cubosomes, works better and causes fewer skin reactions than the old version. It also penetrates and stays in the skin better, promoting hair regrowth. It's safe and could be a good alternative to current treatments.
research Testosterone-stimulated weanlings as an alternative to castrated male rats in the Hershberger anti-androgen assay
Using testosterone-stimulated weanling rats can effectively replace castrated rats for anti-androgen testing, reducing animal stress.
research In vivo alteration of the keratin 17 gene in hair follicles by oligonucleotide‐directed gene targeting
Altering the keratin 17 gene in mice hair follicles caused temporary hair issues, but changes were minimal and short-lived.
research COMPARATIVE STUDY ON THERAPEUTIC EFFICACY OF MINOXIDIL AND PLATELET-RICH PLASMA EXOSOME IN ANDROGENETIC ALOPECIA MICE MODELS
PRP-Exo is more effective than minoxidil for hair growth.
research RU 58841-myristate–prodrug development for topical treatment of acne and androgenetic alopecia.
RUM-loaded SLN shows promise for treating acne and hair loss topically.
research Navigating Rhupus Complexity
Rhupus is a complex syndrome that is hard to diagnose due to unclear clinical criteria.
research The use of a retinoid receptor antagonist in a new model to study vitamin A-dependent developmental events.
The retinoid receptor antagonist effectively disrupts vitamin A-related development in embryos.
research Citrullus colocynthis (L.) Schrad. (Cucurbitaceae)
research Induction of hyperandrogenism and insulin resistance differentially modulates ferroptosis in uterine and placental tissues of pregnant rats
HAIR may cause fetal loss by triggering different cell death processes in the uterus and placenta.
research Navigating Rhupus Complexity
Rhupus is a complex syndrome that combines rheumatoid arthritis and lupus, making diagnosis challenging.
research The antiandrogen cyproterone acetate: discovery, chemistry, basic pharmacology, clinical use and tool in basic research*
research ApoBDs: a paradigm shift from cellular debris to therapeutic vehicles
ApoBDs, once seen as waste, are now viewed as potential tools for disease treatment and tissue repair.
research Can antibiotic‐induced changes in the composition of the hair follicle microbiome regulate human hair growth?
Antibiotics might affect hair growth by changing the bacteria in hair follicles.