32 citations
,
February 2008 in “Journal of the American Academy of Dermatology” KFSD is a genetic disorder causing hair loss and skin issues, with no effective treatment.
29 citations
,
October 2010 in “Journal of Investigative Dermatology” Activating Kras in mouse skin causes excess skin and hair loss.
16 citations
,
November 2022 in “eLife” Both gene and non-gene areas of DNA evolved to make some mammals hairless.
16 citations
,
April 2000 in “Journal of Investigative Dermatology” The AVET system effectively delivers genes to human keratinocytes and may help treat skin diseases.
6 citations
,
November 2008 in “Journal of Dermatological Science” Certain proteins involved in DNA modification may affect the genetic changes in systemic lupus erythematosus and could indicate the disease's activity.
3 citations
,
March 2019 in “Acta histochemica” Angiotensin II is found at higher levels in black sheep skin and may influence coat color.
November 2025 in “Scientific Reports” COVID-19 may cause hair loss by affecting hair follicles.
Hairlessness in mammals is due to complex genetic changes in both genes and regulatory regions.
GPC1 is important for blood vessel growth in hair follicles and could help treat hair loss.
GPC1 is important for hair growth by helping blood vessels form around hair follicles.
GPC1 is important for blood vessel growth in hair follicles and could help treat hair loss.
Glypican-1 is important for hair follicle blood vessel growth and could be a target for treating hair loss.
138 citations
,
June 2023 in “Molecules” Skin pigmentation varies due to genetics, UV exposure, and drugs, with treatments available but requiring medical advice.
1 citations
,
August 2021 in “Arhivʺ vnutrennej mediciny” Hormonal imbalances can cause hair loss, and understanding them can help develop better treatments.
December 1989 in “Inpharma (Balgowlah)” Cyproterone helps women with hair loss caused by genetics. More research is needed to confirm the best dose.
75 citations
,
October 2016 in “Genes & Development” Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.
67 citations
,
June 2018 in “Engineering in Life Sciences” Plant cell culture is a promising method for creating sustainable and high-quality cosmetic ingredients.
60 citations
,
January 2014 in “Anais Brasileiros De Dermatologia” Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.
39 citations
,
September 2012 in “Human Reproduction” Certain genetic variations in the SHBG gene are linked to an increased or decreased risk of PCOS in Mediterranean women.
35 citations
,
January 2013 in “International Journal of Trichology” Kids with early graying hair often have low levels of calcium, ferritin, and vitamin D3.
28 citations
,
September 2013 in “European Journal of Histochemistry” Keratins in Malayan pangolins vary by region, suggesting scales evolved from the tail towards the head.
23 citations
,
November 2020 in “Central-European Journal of Immunology/Central European Journal of Immunology” Alopecia areata, a type of hair loss, is likely an autoimmune disease with a genetic link, but its exact cause is still unknown.
20 citations
,
June 2010 in “Genes and Immunity” Blood tests can help understand the genetic differences in people with alopecia areata, including how severe it is and if it's inherited.
11 citations
,
March 2014 in “Journal of Investigative Dermatology” Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.
2 citations
,
March 2020 in “International Journal of Molecular Sciences” Topical treatments can deliver active molecules to skin stem cells, potentially helping treat skin and hair disorders, including skin cancers and hair loss.
1 citations
,
June 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” The symposium highlighted the skin's role in sensing itch, pain, touch, and pleasure, and discussed new research and techniques for understanding and treating these sensations.
1 citations
,
August 2025 in “Journal of Investigative Dermatology” Genetic studies on hair traits can improve understanding of health and disease.
August 2025 in “Journal of Ayurveda and Integrated Medical Sciences” Combining Ayurvedic and modern treatments can effectively manage hair loss.
January 2025 in “Clinical Cosmetic and Investigational Dermatology” Genetic testing is crucial for diagnosing rare hair loss disorders.
August 2016 in “Journal of Investigative Dermatology” Researchers found a new genetic mutation linked to a hair condition in a Japanese boy.