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A Controlled Study of the Effects of RU58841, a Non-Steroidal Antiandrogen, on Human Hair Production by Balding Scalp Grafts Maintained on Testosterone-Conditioned Nude Mice

research A controlled study of the effects of RU58841, a non-steroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosterone-conditioned nude mice

10 citations , November 1997 in “British Journal of Dermatology”

RU58841 significantly increases hair growth rate and initiates more hair cycles, but doesn't affect hair thickness, suggesting it could be a new treatment for baldness.

research RU 58841, a new specific topical antiandrogen: A candidate of choice for the treatment of acne, androgenetic alopecia and hirsutism

49 citations , January 1994 in “The Journal of Steroid Biochemistry and Molecular Biology”

RU 58841 may treat acne, hair loss, and excessive hair growth.

research Finasteride 98319‐26‐7

October 2012 in “Sax's Dangerous Properties of Industrial Materials”

research 842Combination therapy with rofecoxib and finasteride in the treatment of men with lower urinary tract symptoms (LUTS)

March 2005 in “European Urology Supplements”

research Spatiotemporal Expression and Haplotypes Identification of KRT84 Gene and Their Association with Wool Traits in Gansu Alpine Fine-Wool Sheep

February 2024 in “Genes”

The KRT84 gene is linked to better wool quality in Gansu Alpine Fine-wool sheep.

research An LRH-RSL4 feedback regulatory loop controls the determinate growth of root hairs in Arabidopsis

5 citations , December 2023 in “Current Biology”

A feedback loop between LRH and RSL4 controls root hair growth in Arabidopsis.

research Phase separation: a new window in RALF signaling

2 citations , June 2024 in “Frontiers in Plant Science”

LLPS is crucial for RALF signaling, aiding plant growth and stress resilience.

research A new mutation Rim3 resembling Re den is mapped close to retinoic acid receptor alpha (Rara) gene on mouse Chromosome 11

76 citations , January 1998 in “Mammalian Genome”

research 441 Anti-melanoma gene signature in dermal sheath fibroblasts from scalp hair follicles in Recessive Dystrophic Epidermolysis Bullosa (RDEB)

November 2024 in “Journal of Investigative Dermatology”

research RU 58841-myristate–prodrug development for topical treatment of acne and androgenetic alopecia.

26 citations , January 2005 in “PubMed”

RUM-loaded SLN shows promise for treating acne and hair loss topically.

research NUDT15,FTO, andRUNX1genetic variants and thiopurine intolerance among Japanese patients with inflammatory bowel diseases

40 citations , January 2017 in “Intestinal Research”

Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.

research ISID1116 – Novel androgen receptor degrader for androgenetic alopecia (AGA) application

May 2023

research Hereditary vitamin D-resistant rickets (HVDRR) owing to a heterozygous mutation in the vitamin D receptor

37 citations , August 2011 in “Journal of Bone and Mineral Research”

A girl had rickets due to a gene mutation affecting vitamin D response.

research Identification of 736T>A mutation of lipase H in Japanese siblings with autosomal recessive woolly hair

7 citations , February 2011 in “Journal of dermatology”

The 736T>A mutation in the LIPH gene is common in Japanese people with autosomal recessive woolly hair.

Significance of RU58841 as a Therapeutic Agent Affecting Androgen Receptor Molecular Interactions in Human Hair Follicles

research Significance of RU58841 as a therapeutic agent effecting androgen receptor molecular interactions in human hair follicles.

1 citations , January 1995 in “Journal of Investigative Dermatology”

RU58841, a substance from France, can potentially block the effects of hormones that cause hair loss and excessive hair growth, performing better than a similar substance, cyproterone acetate.

research 944 Non-coding double stranded RNA induces retinoic acid synthesis and retinoid signaling to control regeneration

April 2019 in “Journal of Investigative Dermatology”

Non-coding RNA boosts retinoic acid production and signaling, aiding regeneration.

research 43364 Long Term Real-World Patient-Reported Outcomes with Risankizumab in Patients with Moderate to Severe Psoriasis From the CorEvitas Psoriasis Registry

September 2023 in “Journal of the American Academy of Dermatology”

research Citalopram and finasteride with the lot number FI0510058-A have been voluntarily recalled by Greenstone, after a labelling error

April 2011 in “Reactions Weekly”

Hereditary 1,25-Dihydroxyvitamin D-Resistant Rickets (HVDRR): Clinical Heterogeneity and Long-Term Efficacious Management of Eight Patients from Four Unrelated Arab Families with a Loss of Function VDR Mutation

research Hereditary 1,25-dihydroxyvitamin D-resistant rickets (HVDRR): clinical heterogeneity and long-term efficacious management of eight patients from four unrelated Arab families with a loss of function VDR mutation

6 citations , June 2018 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism”

Patients with the same genetic mutation for vitamin D-resistant rickets showed different symptoms but all improved with treatment except for hair loss.

research Solubilization and Solid‐State Characterization of a Poorly Soluble 5‐α Reductase Inhibitor

January 2004 in “Drug Development and Industrial Pharmacy”

GI197111X is best dissolved in Capmul MCM for trials.

research ERULUS Is a Plasma Membrane-Localized Receptor-Like Kinase That Specifies Root Hair Growth by Maintaining Tip-Focused Cytoplasmic Calcium Oscillations

32 citations , May 2018 in “The Plant Cell”

ERULUS is crucial for root hair growth by controlling calcium levels.

research A controlled study of the effects of RU58841, a non-steroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosterone-conditioned nude mice

9 citations , November 1997 in “British Journal of Dermatology”

research Kyoto Rhino Rats Derived by ENU Mutagenesis Undergo Congenital Hair Loss and Exhibit Focal Glomerulosclerosis

9 citations , January 2011 in “EXPERIMENTAL ANIMALS”

A new rat strain with a specific gene mutation causes hair loss and kidney issues.

research Rational Design and Synthesis of 4-((1R,2R)-2-Hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a Novel, Nonsteroidal Androgen Receptor Antagonist Devoid of Phototoxicity for Dermatological Indications

23 citations , October 2008 in “Journal of medicinal chemistry”

PF-998425 is a new, effective, and non-phototoxic treatment for skin conditions related to androgens.

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research A controlled study of the effects of RU58841, a non-steroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosterone-conditioned nude mice

research RU 58841, a new specific topical antiandrogen: A candidate of choice for the treatment of acne, androgenetic alopecia and hirsutism

research Finasteride 98319‐26‐7

research 842Combination therapy with rofecoxib and finasteride in the treatment of men with lower urinary tract symptoms (LUTS)

research Spatiotemporal Expression and Haplotypes Identification of KRT84 Gene and Their Association with Wool Traits in Gansu Alpine Fine-Wool Sheep

research An LRH-RSL4 feedback regulatory loop controls the determinate growth of root hairs in Arabidopsis

research Phase separation: a new window in RALF signaling

research A new mutation Rim3 resembling Re den is mapped close to retinoic acid receptor alpha (Rara) gene on mouse Chromosome 11

research 441 Anti-melanoma gene signature in dermal sheath fibroblasts from scalp hair follicles in Recessive Dystrophic Epidermolysis Bullosa (RDEB)

research RU 58841-myristate–prodrug development for topical treatment of acne and androgenetic alopecia.

research NUDT15,FTO, andRUNX1genetic variants and thiopurine intolerance among Japanese patients with inflammatory bowel diseases

research ISID1116 – Novel androgen receptor degrader for androgenetic alopecia (AGA) application

research Hereditary vitamin D-resistant rickets (HVDRR) owing to a heterozygous mutation in the vitamin D receptor

research Identification of 736T>A mutation of lipase H in Japanese siblings with autosomal recessive woolly hair

research Significance of RU58841 as a therapeutic agent effecting androgen receptor molecular interactions in human hair follicles.

research 944 Non-coding double stranded RNA induces retinoic acid synthesis and retinoid signaling to control regeneration

research 43364 Long Term Real-World Patient-Reported Outcomes with Risankizumab in Patients with Moderate to Severe Psoriasis From the CorEvitas Psoriasis Registry

research Citalopram and finasteride with the lot number FI0510058-A have been voluntarily recalled by Greenstone, after a labelling error

research Hereditary 1,25-dihydroxyvitamin D-resistant rickets (HVDRR): clinical heterogeneity and long-term efficacious management of eight patients from four unrelated Arab families with a loss of function VDR mutation

research Solubilization and Solid‐State Characterization of a Poorly Soluble 5‐α Reductase Inhibitor

research ERULUS Is a Plasma Membrane-Localized Receptor-Like Kinase That Specifies Root Hair Growth by Maintaining Tip-Focused Cytoplasmic Calcium Oscillations

research A controlled study of the effects of RU58841, a non-steroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosterone-conditioned nude mice

research Kyoto Rhino Rats Derived by ENU Mutagenesis Undergo Congenital Hair Loss and Exhibit Focal Glomerulosclerosis

research Rational Design and Synthesis of 4-((1R,2R)-2-Hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a Novel, Nonsteroidal Androgen Receptor Antagonist Devoid of Phototoxicity for Dermatological Indications

research Novel Vitamin D Receptor Mutations in Hereditary Vitamin D Resistant Rickets in Chinese

research Localized variant of junctional epidermolysis bullosa with R795X mutation

research PRX102 Participates in Root Hairs Tip Growth of Rice

research Alternative synthesis of the anti-baldness compound RU58841

research Clinical and genetic findings in a Chinese family with VDR-associated hereditary vitamin D-resistant rickets

research The Auxin-Regulated CrRLK1L Kinase ERULUS Controls Cell Wall Composition during Root Hair Tip Growth