28 citations
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March 1993 in “Journal of Cell Science” Keratins K4 and K13 form stable dimers in mature esophageal cells, aiding cell stability.
27 citations
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April 1978 in “Journal of Forensic Sciences” Enzyme typing can reliably characterize human hair.
25 citations
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October 2015 in “Dermatology” Dapsone improved pustular psoriasis in patients who didn't respond to other treatments and is considered a well-tolerated option.
25 citations
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January 2000 in “Hormone Research in Paediatrics” Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.
25 citations
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July 1994 in “Journal of Cell Science” Immortalized rat dermal papilla cells can still induce hair growth.
24 citations
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November 2015 in “Annals of Nutrition and Metabolism” Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.
23 citations
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March 2009 in “Skin Pharmacology and Physiology” Hair loss in men and women is linked to high stress hormone levels and other hormonal imbalances, suggesting treatments should be customized to each person's hormones.
23 citations
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November 1986 in “Pediatrics” Minoxidil, when used with a diuretic and β-blocking agent, can safely lower blood pressure in most children with severe hypertension due to kidney disease, with minimal side effects.
22 citations
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April 2015 in “Current problems in dermatology” Human hair follicles have a unique metabolism that changes between growth stages and may contribute to baldness.
22 citations
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January 1999 in “Dermatology” The condition might be caused by genetic changes after birth.
22 citations
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January 1987 in “Dermatology” Hair loss is common, influenced by genetics and androgens, and can affect mental health.
22 citations
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April 1967 in “Australian Journal of Zoology” Southern elephant seals develop hair follicles and skin layers before birth, with moulting starting a week after birth and finishing in three weeks.
21 citations
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January 2016 in “NeuroImmunoModulation” Hair cortisol levels can indicate stress over the past three months.
21 citations
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January 2015 in “Oncology Research and Treatment” Scalp cooling can prevent hair loss in 65% of chemotherapy patients, especially effective in breast cancer patients and certain chemotherapy types.
21 citations
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October 2009 in “Dermatology” Men with male pattern hair loss have different levels of certain hormones compared to men without hair loss.
21 citations
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January 2006 in “Pediatrics” Some diseases can improve the outcomes of other diseases, leading to new treatment possibilities.
21 citations
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January 2006 in “Hormone Research in Paediatrics” A mutation in the VDR gene affects hair cycling without needing ligand binding.
20 citations
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January 2015 in “Current problems in dermatology” Hair gets thinner, grayer, and changes texture with age due to genetics, environment, and cellular changes, affecting the growth cycle.
20 citations
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May 1998 in “PEDIATRICS” African-American girls tend to start puberty earlier than white girls, possibly due to increased androgen production.
20 citations
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January 1995 in “Cells tissues organs” Changing light periods synchronized wool growth cycles in sheep.
19 citations
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January 2001 in “Dermatology + psychosomatics” The review concluded that male pattern baldness is mostly seen negatively, affecting attractiveness and social appeal.
18 citations
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March 2010 in “Gynecologic and obstetric investigation” The oral contraceptive alone is the preferred treatment for hirsutism, as adding the GnRH analog showed no significant benefit.
18 citations
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March 2009 in “Skin pharmacology and physiology” Sunlight damages hair, causing cuticle loss, protein changes, and discoloration.
18 citations
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January 1994 in “Skin Pharmacology and Physiology” Human dermal fibroblasts and hair papilla cells help outer root sheath cells grow and develop properly.
18 citations
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January 1992 in “Dermatology” A 4-year-old girl has a rare condition causing hairlessness and skin bumps, but normal teeth and sweating.
18 citations
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January 1977 in “Annals of Nutrition and Metabolism” Genetic disorders can disrupt mineral and trace element metabolism, affecting health.
18 citations
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January 1976 in “Clinical Science” Minoxidil effectively lowers severe high blood pressure but may cause side effects like increased hair growth.
17 citations
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November 2018 in “Dermatology” Most patients with frontal fibrosing alopecia had facial bumps, with Hispanic/Latino and premenopausal women being more affected, suggesting a more severe condition.
17 citations
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October 1997 in “Australian Journal of Agricultural Research” Stocking rate affects wool follicle inactivity, not Merino strain.
17 citations
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January 1984 in “Psychotherapy and psychosomatics” Antiandrogen treatment can reduce sexual enjoyment in women with excess male hormones, especially those in stable relationships.