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January 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Vitamin D Receptor is crucial for normal skin and hair growth.
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January 2020 in “Indian Journal of Dermatology” Certain gene variations in the Vitamin D Receptor are linked to higher risk of female hair loss.
April 2025 in “Frontiers in Pharmacology” Canagliflozin helps overcome progestin resistance in certain endometrial cancer cells.
February 2026 in “Advanced Science” TTNPB helps turn stem cells into neural stem cells, improving depression-like behaviors in rats.
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July 2023 in “Nutrients” Vitamin D may help reduce thyroid antibodies and improve thyroid function in Hashimoto's Thyroiditis.
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March 2021 in “Experimental and Therapeutic Medicine” Isotretinoin can cause serious birth defects and needs careful use, especially in pregnant women.
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July 2018 in “Our Dermatology Online” Some vitamins and minerals are important for preventing hair loss, but treating hair loss with them without a known deficiency is not proven effective.
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January 2025 in “Burns & Trauma” PPAR activation can improve diabetic wound healing by enhancing blood vessel function.
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December 2020 in “Tissue Barriers” Loricrin affects skin immune function and homeostasis.
February 2026 in “Exploration” Advancements in gene therapy, stem cells, and biomaterials show promise for reducing scarring in wound healing, but face clinical challenges.
June 2024 in “Ecotoxicology and Environmental Safety” Finasteride harms Daphnia magna's reproduction, growth, and metabolism.
October 2023 in “Apollo medicine” The skin acts like an endocrine organ, producing hormones that affect various body functions and skin health, and understanding this can lead to new treatments.
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October 2000 in “Nature” RXRα is crucial for hair growth and skin cell function.
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May 2002 in “PubMed” LGD1069 effectively prevents breast tumors in mice without toxicity.
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August 1995 in “British journal of dermatology/British journal of dermatology, Supplement” RXR-alpha is strongly expressed in both normal and psoriatic skin and may help in skin cell differentiation and hair growth.
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January 2013 in “European Journal of Dermatology” Alitretinoin may help treat alopecia areata.
RXR and RAR proteins in skin may help with cell growth, hair growth, and gland function.
April 2016 in “Journal of Investigative Dermatology” Lithocholic acid helps hair growth and regeneration in alopecia by activating vitamin D receptors.
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June 2019 in “Scientific Reports” Increased PPARGC1α relates to hair thinning in common baldness.
Retinoids can help treat skin pigmentation disorders by affecting melanin production.
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September 2021 in “Cureus” The rs1128977 gene variant may affect cholesterol and body measurements.
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August 2015 in “Biochemical and Biophysical Research Communications” XEDAR triggers a specific signaling pathway in cells.
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March 2022 in “Plant Cell & Environment” The protein AtRXR3 limits root hair growth in Arabidopsis, affecting phosphorus uptake.
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November 2004 in “Blood” RXRa is crucial for Th2 immune cell development and may link nutrition to immune health.
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November 2008 in “Acta crystallographica” Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.
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May 2016 in “Progress in Biophysics & Molecular Biology” R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.
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October 2001 in “Genes & Development” The mutated hairless gene causes hair loss by acting as a new type of corepressor affecting thyroid hormone receptors.
The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.
510 citations
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August 2006 in “Endocrinology” The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.