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17β-estradiol boosts APE1/Ref-1 secretion in cells and mice via a calcium-dependent pathway.

A 15-year-old girl with rare reproductive disorders received hormone therapy to develop secondary sexual traits, but infertility persisted.

The research found how GPCR Class A Rhodopsin receptors are related and suggested possible substances they interact with.

New mutations in KRT83 and KRT86 are linked to the hair disorder monilethrix.

A new gene causes hairlessness and skin cysts in rats.

Different mutations in the 5 alpha-reductase-2 gene were found in affected individuals in the Dominican Republic, suggesting no common ancestry.

The treatment was not recommended due to limited effectiveness and significant side effects.

Ritlecitinib is being tested for safety and effectiveness in young children with severe alopecia areata.

Ritlecitinib improves hair growth and quality of life in severe alopecia areata with longer use.

A specific gene mutation causes vitamin D-resistant rickets and hair loss.

The inhibitor affects androgen metabolism but not ovarian function.

Regional prescribing of ritlecitinib mostly follows national guidance, but psychological assessments and consistent scoring need improvement.

A rare skin condition in a 17-year-old was diagnosed late, stressing the need for careful evaluation and genetic testing.

Patients with RASopathies have a higher risk of autoimmune disorders and should be routinely screened.

Certain genetic variations in the RAB5B gene are linked to a higher risk of polycystic ovary syndrome in Chinese Han women.

CXCR2 in skin cells promotes tumor growth.

New mutations in the EBP gene cause CDPX2, affecting bones, skin, eyes, and hair, with females generally less affected than males.

Skin changes in Pseudoxanthoma elasticum patients can indicate the severity of related health issues.

Some prostate cancers have gene changes that may affect treatment with certain drugs.

A rare genetic mutation causes resistance to vitamin D, leading to severe rickets and requires high doses of calcium and vitamin D for management.

Topical ruxolitinib failed to regrow hair in a 66-year-old with alopecia areata.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

A new mutation in the TRPS1 gene was found in a Ukrainian girl with Trichorhinophalangeal syndrome type I.

Scientists at the University of Michigan Medical School successfully created a special compound that can be used to improve imaging of prostate cancer.

CARASIL, a rare genetic disorder, was confirmed in an Arabic woman, highlighting its rarity and need for stroke prevention.

Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.

Vitamin D receptor mutations can cause alopecia by affecting hair growth genes.

Activated ras can protect kidney cells from a certain substance that causes cell death.

Female rats showed more panic-related behavior than males, influenced by hormonal cycles and certain drugs.