A Case of Topical Ruxolitinib Treatment Failure in Alopecia Areata

    June 2017 in “ Journal of cutaneous medicine and surgery ”
    Maya Deeb, Renée A. Beach
    TLDR Topical ruxolitinib failed to regrow hair in a 66-year-old with alopecia areata.
    The document reported a case where topical ruxolitinib (0.6% cream) failed to induce hair growth in a 66-year-old patient with alopecia areata (AA). This contrasted with a previous success in a young patient with alopecia universalis (AU). The study highlighted the need to understand the factors contributing to variations in treatment response, including patient-specific intrinsic factors and treatment regimen-related extrinsic factors. It also suggested that oral administration of ruxolitinib might be more effective for severe cases of AA, AT, and AU compared to topical application.
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      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

      community Ruxolitinib - Start of a case study

      in Research/Science  10 upvotes 1 year ago
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      in Research/Science  1 upvotes 3 days ago
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