2 citations
,
November 2017 in “Biotechnology Letters” Researchers found four natural compounds that can change DHT levels in prostate cancer cells.
52 citations
,
March 1987 in “Journal of the American Academy of Dermatology” High DHEA-S levels may cause hair loss in young men.
23 citations
,
September 2021 in “Frontiers in Cellular and Infection Microbiology” Testosterone's effects on COVID-19 are unclear and need more research.
September 1978 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry”
45 citations
,
March 2015 in “Clinical Endocrinology” Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.
Antiandrogens and finasteride may help treat excess hair and hair loss in women.
7 citations
,
January 2021 in “The Journal of Sexual Medicine” Testosterone with dutasteride improves muscle strength and body composition in trans men.
Testosterone raises blood pressure by affecting kidney function and brain gene regulation over time.
57 citations
,
August 1995 in “British Journal of Dermatology” Acne severity is linked to higher levels of certain androgenic hormones, even when those levels are within the normal range.
192 citations
,
January 1976 in “The Journal of Clinical Endocrinology & Metabolism” Androgen levels increase with puberty and are linked to sexual hair development.
56 citations
,
January 1999 in “The Analyst” The method accurately measures certain steroids in human hair, showing different levels in males and females.
8 citations
,
March 2012 in “Mass spectrometry letters” The S9 fraction with GC-IDMS is effective for measuring 5α-reductase activity.
5 citations
,
June 2004 in “The Journal of The British Menopause Society” Testosterone therapy can improve sexual satisfaction and mood in surgically menopausal women when used with estrogen, but its long-term safety and effects on naturally menopausal and premenopausal women are unclear.
January 2004 in “DOAJ (DOAJ: Directory of Open Access Journals)” Men with androgenetic alopecia do not have elevated DHEA-S levels.
February 2017 in “The Journal of Sexual Medicine” Long-term testosterone treatment helps men with low testosterone levels lose weight.
51 citations
,
July 2013 in “Brain Research” Testosterone needs to be converted to DHT to reduce stress response in male rats.
4 citations
,
May 2024 in “Steroids” The method accurately measures sex hormones in human plasma but can have small errors.
6 citations
,
May 2016 in “Urolithiasis” Balding and low testosterone increase risk of urinary stones.
124 citations
,
March 2012 in “JAMA” Testosterone's muscle-building effects do not require its conversion to DHT.
33 citations
,
December 2005 in “British Journal of Clinical Pharmacology” The new testosterone patch works as well as the gel.
4 citations
,
January 2013 in “PubMed” Testosterone and finasteride raise insulin and zinc, lower chromium in male rats.
16 citations
,
December 2010 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” Normal levels for certain hormones in Chinese women of reproductive age were identified.
March 2015 in “Journal für Kardiologie (Krause & Pachernegg GmbH)” Testosterone affects skin by increasing oil production and influences hair growth.
June 2025 in “JCEM Case Reports” False high testosterone levels were corrected using a more accurate test.
2 citations
,
December 2017 in “Theriogenology” Testosterone increases acidification in the vas deferens by up-regulating V-ATPase.
April 2019 in “Journal of Investigative Dermatology” Testosterone affects androgen receptors and lipid storage in cells, while DHEA does not convert to testosterone or affect these receptors in the same way.
16 citations
,
October 2007 in “Andrologia” DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.
29 citations
,
November 1975 in “Clinics in endocrinology and metabolism” Testosterone is made by Leydig cells, is active when not bound to proteins, and works by binding to receptors in muscles and other tissues.
59 citations
,
September 2003 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Epitestosterone may counteract testosterone's effects and has roles in body processes like prostate growth and hair distribution.
Women with androgenetic alopecia (hair loss) have normal prostate specific antigen levels but higher testosterone levels.