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research Applications of Mesenchymal Stem Cells in Skin Regeneration and Rejuvenation

76 citations , February 2021 in “International Journal of Molecular Sciences”

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Fibromodulin Deficiency Alters Temporospatial Expression Patterns of Transforming Growth Factor-β Ligands and Receptors During Adult Mouse Skin Wound Healing

research Fibromodulin-Deficiency Alters Temporospatial Expression Patterns of Transforming Growth Factor-β Ligands and Receptors during Adult Mouse Skin Wound Healing

32 citations , March 2014 in “PLOS ONE”

Mice lacking fibromodulin have disrupted healing patterns, leading to abnormal skin repair and scarring.

Motoneuron-Specific PTEN Deletion in Mice Induces Neuronal Hypertrophy and Regeneration After Facial Nerve Injury

research Motoneuron-Specific PTEN Deletion in Mice Induces Neuronal Hypertrophy and Also Regeneration after Facial Nerve Injury

6 citations , February 2022 in “The journal of neuroscience/The Journal of neuroscience”

Deleting the PTEN gene in mice causes nerve cells to grow larger and heal better after injury, but may cause overgrowth and hair loss in older mice.

research Langerin+ Dendritic Cells in Cutaneous Fibrosis: The TGF-β1 Signaling Axis

October 2025 in “Clinical Cosmetic and Investigational Dermatology”

Targeting specific cell interactions may help treat skin fibrosis.

research Finasteride 98319‐26‐7

October 2012 in “Sax's Dangerous Properties of Industrial Materials”

research 17beta Hydroxysteroid Dehydrogenase Type 3 Inhibitors

January 2004

The document's conclusion cannot be provided because the document is not available or cannot be read.

research LB793 A phase 1, open-Label, single ascending dose study in healthy subjects of the safety, tolerability and pharmacokinetics of ASLAN004, a novel IgG anti-IL-13 receptor alpha 1 Inhibitor

1 citations , August 2021 in “Journal of Investigative Dermatology”

ASLAN004 was safe and well-tolerated, supporting further development for treating certain diseases.

research Citalopram and finasteride with the lot number FI0510058-A have been voluntarily recalled by Greenstone, after a labelling error

April 2011 in “Reactions Weekly”

Baseline Distribution of Eyebrow and Eyelash Loss by Severity of Scalp Hair Loss in Phase 3 Trials of Baricitinib for Alopecia Areata

research 41247 Baseline distribution of eyebrow and eyelash loss by severity of scalp hair loss in phase 3 trials of baricitinib for alopecia areata

September 2023 in “Journal of The American Academy of Dermatology”

The document's conclusion cannot be provided because the content is not available.

Single Nucleotide Polymorphisms Associated with Elevated Alanine Aminotransferase in Patients Receiving Asunaprevir Plus Daclatasvir Combination Therapy for Chronic Hepatitis C

research Single nucleotide polymorphisms associated with elevated alanine aminotransferase in patients receiving asunaprevir plus daclatasvir combination therapy for chronic hepatitis C

2 citations , July 2019 in “PLOS ONE”

Certain genetic variations are linked to higher liver enzyme levels in patients treated for chronic hepatitis C with specific drugs.

research Two novel BTD mutations causing profound biotinidase deficiency in a Chinese patient

3 citations , January 2021 in “Molecular genetics & genomic medicine”

The study found two new mutations in a Chinese patient with severe biotinidase deficiency.

research BindingDB Entry 50021519: Discovery of (2S)-N-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-3-(6-(4-cyanophenyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)-2-hydroxy-2-methylpropanamide as a Highly Potent and Selective Topical Androgen Receptor Antagonist for Androgenetic Alopecia Treatment.

January 2025

research Targeting Superficial or Nodular Basal Cell Carcinoma with Topically Formulated Small Molecule Inhibitor of Smoothened

63 citations , May 2011 in “Clinical cancer research”

The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.

research Data from Targeting Superficial or Nodular Basal Cell Carcinoma with Topically Formulated Small Molecule Inhibitor of Smoothened

March 2023

The treatment was ineffective in humans.

Androgen Receptor Gene Polymorphism (SNP RS6152) – Its Relationship to Androgen-Sensitive Genes Expression in Benign Prostatic Hyperplasia, Carcinoma of the Prostate, and Androgenetic Alopecia

research 409 ANDROGEN RECEPTOR GENE POLYMORPHISM (SNP RS6152) – ITS RELATIONSHIP TO ANDROGEN-SENSITIVE GENES EXPRESSION IN BENIGN PROSTATIC HYPERPLASIA, CARCINOMA OF THE PROSTATE AND ANDROGENETIC ALOPECIA

March 2011 in “European Urology Supplements”

Gene variation affects prostate issues and hair loss.

research ISID1116 – Novel androgen receptor degrader for androgenetic alopecia (AGA) application

May 2023

research 708 SIG-1451: A topical anti-inflammatory new chemical entity for atopic dermatitis (AD)

April 2017 in “Journal of Investigative Dermatology”

SIG-1451 could be a promising new treatment for atopic dermatitis.

research The senescence-like activity of BMS-470539 is associated with anti-fibrotic actions in models of dermal fibrosis

September 2025 in “Arthritis Research & Therapy”

BMS-470539 reduces skin fibrosis and inflammation.

GBP1 as a Machine Learning-Prioritized Biomarker and Therapeutic Target for Epstein-Barr Virus-Induced Clear Cell Renal Cell Carcinoma: Multi-Omics Causal Validation

research GBP1 as a machine learning-prioritized biomarker and therapeutic target for epstein-barr virus-induced clear cell renal cell carcinoma: multi-omics causal validation

December 2025 in “International Journal of Surgery”

GBP1 is a key target for treating Epstein-Barr virus-related kidney cancer, and finasteride may help.

research HSD3B1 Genotypes Conferring Adrenal-Restrictive and Adrenal-Permissive Phenotypes in Prostate Cancer and Beyond

30 citations , July 2019 in “Endocrinology”

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

research Association study reveals a susceptibility locus with male pattern baldness in the Han Chinese population

September 2024 in “Frontiers in Genetics”

A specific genetic marker is linked to male pattern baldness in Han Chinese men.

research 709 Nitric oxide-releasing topical therapeutic agent for atopic dermatitis

April 2017 in “Journal of Investigative Dermatology”

SB414 may be an effective treatment for atopic dermatitis by reducing swelling and bacterial infection.

Genotyping Of The Rs1800440 Polymorphism In CYP1B1 Gene And The Rs9258883 Polymorphism In HLA-B Gene In A Spanish Cohort Of 223 Patients With Frontal Fibrosing Alopecia

research Genotyping of the rs1800440 Polymorphism in CYP1B1 Gene and the rs9258883 Polymorphism in HLA-B Gene in a Spanish Cohort of 223 Patients with Frontal Fibrosing Alopecia

1 citations , September 2023 in “Acta dermato-venereologica”

Certain genetic variants are linked to frontal fibrosing alopecia in Spanish patients.

research Pseudallescheria boydii infection associated with IgG4-related disease

3 citations , September 2022 in “European Journal of Dermatology”

This study focused on a family with Junctional epidermolysis bullosa (JEB), a rare genetic disorder, to confirm their diagnosis and identify the pathogenic variant. Researchers collected clinical data and DNA from family members, utilizing whole-exome sequencing and Sanger sequencing to detect gene variants. They discovered a novel splice-site variant (c.629-12T>G) in the LAMB3 gene present in all patients, confirming it as a pathogenic variant. The study concluded that diagnosing JEB should rely on gene sequencing, as splice site variants can also lead to the disease.

research Bicalutamide

January 2025

research The synthesis of (−)-4-methyl-8-chloro-trans-1,2,3,4,4a,5,6,10b-octahydrobenzo-[f]-quinolin-3-one-[3-14C] (LY300502-14C]) via a circuitous route

3 citations , October 1994 in “Journal of Labelled Compounds and Radiopharmaceuticals”

Scientists made a carbon-14 labeled version of a drug with a 48% yield and over 99% purity.

research Male pattern hair loss - rh79g

December 2025 in “ILDS-DEV”

research Supplementary Material for: The Role of Fibrosis in Androgenetic Alopecia: Mechanisms and Implications

January 2025

Combining anti-androgenic, anti-inflammatory, and anti-fibrotic treatments may improve hair loss outcomes.

research De novo variation in ARID1B gene causes Coffin-Siris syndrome 1 in a Chinese family with excessive early-onset high myopia

3 citations , May 2024 in “BMC Medical Genomics”

A new ARID1B gene variation causes Coffin-Siris syndrome 1 and early high myopia in a Chinese family.

research A novel MBTPS2 variant associated with BRESHECK syndrome impairs sterol‐regulated transcription and the endoplasmic reticulum stress response

5 citations , October 2021 in “American Journal of Medical Genetics Part A”

A new genetic variant causes BRESHECK syndrome by disrupting cell growth and stress response.

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