research High-resolution structures of mutants of residues that affect access to the ligand-binding cavity of human lipocalin-type prostaglandin D synthase
Mutations in the enzyme don't significantly change how it binds to its specific substances.
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research Structure-guided manipulation of the regioselectivity of the cyclosporine A hydroxylase CYP-sb21 from Sebekia benihana
Scientists improved an enzyme to better produce a hair growth-promoting chemical from an immunosuppressant.
research Isolation and structural identification of a novel minoxidil analogue in an illegal dietary supplement: triaminodil
A new minoxidil-like substance, triaminodil, was found in an illegal hair growth supplement.
research A Clinical Study to Evaluate Effectiveness of Rosmarinus officinalis Mother Tincture in Improving Hair Volume and Density in Patients with Diffuse Cyclical Hair Loss Through Hair Shedding Visual Scale and Ponytail Thickness Test
Rosmarinus officinalis tincture significantly improves hair volume and density.
research Trichofolliculoma of the Scalp: A Rare Case Report
Trichofolliculoma is a rare, benign scalp tumor that can be cured by surgical removal.
research Assessment of scalp hair survivin in patients with premature greying of hair
Examining Survivin levels may help understand premature greying of hair.
research Hair: A Review of Prominent Scalp Hair Changes throughout a Females’ Life
Women's hair gets thinner and grayer as they age, with treatments available for hair loss and graying.
research Structural Requirements of Minoxidil Analogs for Enhancing Lysyl Hydroxylase Inhibitory Activity
Minoxidil analogs can be improved for hair growth inhibition by modifying specific parts of their structure.
research Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria
The research found that PCOS has common genetic factors regardless of how it is diagnosed and is linked to metabolic and reproductive issues.
research Dermoscopic Approach to a Small Round to Oval Hairless Patch on the Scalp
Dermoscopic examination helps diagnose different types of hair loss conditions by showing specific patterns.
research Sequential Scalp Assessment in Hair Regeneration Therapy Using an Adipose-Derived Stem Cell–Conditioned Medium
Using a special stem cell formula on the scalp once a month for six months helped people with hair loss grow more hair.
research Iron deficiency and diffuse nonscarring scalp alopecia in women: More pieces to the puzzle
The conclusion suggests a possible link between iron levels and hair health in women, recommending further research on iron supplementation for hair loss.
research Increased Scalp Skin and Serum 5a-Reductase Reduced Androgens in a Man Relevant to the Acquired Progressive Kinky Hair Disorder and Developing Androgenetic Alopecia
Reduced androgens linked to kinky hair disorder and hair loss; 5a-reductase inhibitors may help.
research An efficient method for isolation of hair papillae and follicle epithelium from human scalp specimens
A new method helps isolate key hair components to study hair growth and loss.
research Enhanced Follicular Delivery of Finasteride to Human Scalp Skin Using Heat and Chemical Penetration Enhancers
Heat and chemicals improve finasteride delivery to scalp and hair follicles, potentially enhancing treatment for hair loss.
research Formulation and evaluation of beta-sitosterol enriched herbal scalp serum
The herbal scalp serum may help hair growth by reducing DHT levels.
research Necrobiosis lipoidica of the scalp
A rare scalp condition caused scarring hair loss in a woman, improved slightly with treatment.
research 1319 Claudin-1 and -3 maintain proper hair follicle structure and regulate telogen effluvium
Claudin-1 and Claudin-3 are crucial for keeping hair follicle structure and preventing a type of hair loss called telogen effluvium.
research The metabolism of testosterone by dermal papilla cells cultured from scalp follicles of men with androgenetic alopecia
Testosterone metabolism in balding scalp cells may not be the main cause of hair loss.
research The growth of human scalp hair in females using visible red light laser and LED sources
Red light therapy is safe and effectively increases hair growth in women with hair loss.
research Dermal Papilla Cells Improve the Wound Healing Process and Generate Hair Bud-Like Structures in Grafted Skin Substitutes Using Hair Follicle Stem Cells
Dermal papilla cells help wounds heal better and can potentially grow new hair.
research Hair follicles as a target structure for nanoparticles
Nanoparticles around 600-700 nm can effectively enter and stay in hair follicles for days, which may help in delivering drugs to specific cells.
research Mapping the molecular and structural specialization of the skin basement membrane for inter-tissue interactions
The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.
research A pilot split-scalp study of combined fractional radiofrequency microneedling and 5% topical minoxidil in treating male pattern hair loss
Combined microneedling and minoxidil improves hair growth more than minoxidil alone.
research Trichoscopy of Dark Scalp
Trichoscopy helps diagnose hair and scalp disorders in dark-skinned people by identifying unique patterns.
research Morphological and morphometric study of the androgenetic alopecic scalp using two- and three-dimensional analysis comparing regional differences
The study found that balding scalps have more thin hairs and larger oil glands, which might contribute to skin conditions related to hair loss.
research Disulfide Cross-Linked Network Structure of Intermediate Filament and Matrix in Hair and Wool Cortices
Hair and wool strength is affected by the number and type of bonds in their protein structures, with hair having more protein aggregates than wool.
research Three-Dimensional Proteome-Wide Scale Screening for the 5-Alpha Reductase Inhibitor Finasteride: Identification of a Novel Off-Target
Finasteride may affect PNMT, causing side effects.
research Mapping the molecular and structural specialization of the skin basement membrane for inter-tissue interactions
The skin's basement membrane is specially designed to support different types of connections between skin layers and hair follicles.
research Sparse haplotype-based fine-scale local ancestry inference at scale reveals recent selection on immune responses
Recent selection on immune response genes was identified across seven ethnicities.