16 citations
,
January 2016 in “Annals of Dermatology” Green tea component EGCG may help prevent hair loss by changing microRNA levels in certain scalp cells.
11 citations
,
January 2001 in “Cambridge University Press eBooks” Androgens can cause hair growth in some areas but hair loss on the scalp.
8 citations
,
January 2020 in “International Journal of Trichology” Silymarin improves hair follicle health better than vitamin C by boosting cell growth and reducing oxidative stress.
2 citations
,
September 2023 in “Cosmetics” Cannabinoids may help some skin conditions but more research is needed.
37 citations
,
January 2016 in “Drug design, development and therapy” Tofacitinib citrate is effective for moderate-to-severe chronic plaque psoriasis but has safety concerns at higher doses.
18 citations
,
August 1985 in “European journal of endocrinology” Cyproterone acetate is effective for treating hirsutism, but some patients may feel worse on low-dose maintenance therapy.
16 citations
,
January 2010 in “Drug Metabolism and Pharmacokinetics” Finasteride's effect on hair loss and prostate enlargement depends on its binding to an enzyme, with maximum impact at 0.2 mg dose.
2 citations
,
May 2021 in “Clinical Pharmacology in Drug Development” Clascoterone is safe for the heart, even at high doses.
February 2026 in “Journal of Dermatological Treatment” CG2001 is safe and well-tolerated for treating hair loss, with fewer side effects than oral finasteride.
September 2023 in “Clinical, cosmetic and investigational dermatology” A new surgical method using special sutures significantly reduced wound size and prevented disease return in patients with a scarring scalp condition.
March 2004 in “Current Sexual Health Reports” Testosterone's role in women's sex drive is unclear and needs more research, as low levels don't always mean less sexual interest and high levels can cause side effects.
23 citations
,
September 2016 in “BMC musculoskeletal disorders” Methotrexate for rheumatoid arthritis often causes side effects like diarrhea, fatigue, and hair loss, especially at higher doses.
June 2008 in “British Journal of Dermatology” Herpes gestationis is linked to certain antigens, atopic eczema affects T cell populations and may be eased by breastfeeding, higher doses of anti-androgen treatment can improve androgenic alopecia, topical minoxidil increases hair thickness, long-term methotrexate therapy can cause liver fibrosis in psoriasis patients, and Lichen Sclerosus et Atrophicus patients aren't at higher risk for autoimmune disorders.
33 citations
,
April 2009 in “Clinical and Experimental Dermatology” Psychological factors like depression may be more important than zinc, folate, and vitamin B12 levels in causing scalp pain in people with hair loss.
6 citations
,
May 2021 in “Aesthetic Surgery Journal” Higher cell number PRP improves hair density and diameter more than lower cell number PRP.
March 2021 in “Clin-Alert” The FDA warned about safety issues with remdesivir and tofacitinib, finasteride is linked to suicidality, potent topical corticosteroids increase osteoporosis risk, henna can cause hemolysis in G6PD deficiency, chemotherapeutic agents can cause adverse reactions, drug interactions are common in cancer patients, ketamine can reduce at-risk drinking, high dose of anticholinergics increases dementia risk in Parkinson's patients, and prenatal exposure to second-generation antipsychotics increases pregnancy complications.
April 2023 in “Dermatology and therapy” Most patients stop using topical minoxidil due to side effects.
November 2025 in “Journal of Family Medicine and Primary Care” Low-dose minoxidil effectively enhances facial hair with minimal side effects.
January 1998 in “NEJM Journal Watch” Finasteride increases hair count in men with hair loss, but the effect isn't permanent and hair loss returns if treatment stops.
1 citations
,
July 2020 in “International journal of radiology & radiation therapy” Partial hair-sparing brain radiotherapy is possible and doesn't affect cancer control but still causes noticeable hair loss.
2 citations
,
October 2020 in “The Journal of clinical and aesthetic dermatology” The herbal mix (Biochanin A, Acetyl tetrapeptide-3, and Ginseng Extracts) and the 3% Minoxidil solution are equally effective in treating hair loss, but the herbal mix has fewer side effects.
January 2025 in “International Journal of Trichology” Topical spironolactone and minoxidil both effectively treat female hair loss, but spironolactone has fewer side effects.
Oral spironolactone may be effective for female pattern hair loss with a low rate of side effects.
61 citations
,
July 2011 in “PLOS ONE” Spermidine may help reduce hair loss and deserves further testing as a treatment.
26 citations
,
October 1999 in “Archives of Dermatology” Curly hair in certain scalp areas can be an early sign of hair loss.
13 citations
,
February 2025 in “Journal of the European Academy of Dermatology and Venereology” Ritlecitinib shows promise for treating alopecia areata, especially with early and extended treatment.
4 citations
,
March 2023 in “Current Oncology” Scalp cooling is the only FDA-approved method to prevent hair loss from chemotherapy, but other treatments like minoxidil and PRP are being tested.
1 citations
,
January 2022 in “Transgender health” Hormone therapy in transgender individuals can increase acne and affect hair growth and loss.
1 citations
,
December 2025 in “Diagnostics” Stopping zolpidem improved hair loss caused by self-inflicted scalp injuries during sleep.
1 citations
,
January 2013 in “Advanced Biomedical Research” Men with more severe hair loss had a lower risk of schizophrenia, but hair loss and testosterone levels were not linked.