February 2026 in “Preprints.org” New therapies and personalized approaches improve wound healing and patient quality of life.
102 citations
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April 2014 in “PloS one” Wharton’s Jelly stem cells from the umbilical cord improve skin healing and hair growth without scarring.
51 citations
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January 2006 in “Wound Repair and Regeneration” MRL/MpJ mice's skin wounds heal with scars, unlike their ear wounds which can regenerate.
11 citations
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January 1988 in “PubMed” Epidermal cell extracts improve skin healing and reduce scarring.
January 2025 in “Regenerative Biomaterials” The hydrogel helps reduce scarring and improve wound healing by releasing salvianolic acid B in acidic conditions.
13 citations
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April 2025 in “International Journal of Nanomedicine” The new gallic acid hydrogel speeds up wound healing and reduces scarring.
10 citations
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January 2018 in “Organogenesis” Porcine acellular dermal matrix treatment helps wounds heal faster and reduces scarring by affecting Jag1 in skin stem cells.
2 citations
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July 2025 in “Journal of Plastic Reconstructive & Aesthetic Surgery” Hair follicles can improve wound healing and reduce scarring.
February 2026 in “Exploration” Advancements in gene therapy, stem cells, and biomaterials show promise for reducing scarring in wound healing, but face clinical challenges.
8 citations
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May 2021 in “Applied Materials Today” New nano composite helps reduce scars and regrow hair during burn wound healing.
April 2023 in “The Egyptian Journal of Histology” Platelet-rich plasma helps heal second-degree burns and reduces scarring.
January 2025 in “Stem Cell Reviews and Reports”
115 citations
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December 2017 in “Wiley Interdisciplinary Reviews-Developmental Biology” Skin cells called dermal fibroblasts are important for skin growth, hair growth, and wound healing.
18 citations
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January 2022 in “Oxidative Medicine and Cellular Longevity” Fibroblasts are crucial in scar formation and wound healing, with potential therapies aiming for scarless healing.
13 citations
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January 2020 in “Scientific Reports” The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.
10 citations
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July 2025 in “Stem Cell Research & Therapy” Engineering strategies improve stem cells' ability to heal wounds effectively.
Reprogramming adult fibroblasts may enable scar-free healing.
January 2025 in “PLoS ONE” Aligned membranes improve wound healing by reducing scars and promoting skin regeneration.
August 2022 in “Research Square (Research Square)” Implanted special stem cells from hair follicles helped heal wounds faster and with less scarring in mice.
163 citations
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October 2001 in “EMBO journal” Overexpressing follistatin in mice delays wound healing and reduces scar size.
108 citations
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January 2023 in “Journal of Tissue Engineering” Scarless skin repair is possible by understanding and balancing wound healing mechanisms.
66 citations
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July 2015 in “Organogenesis” Wnt signaling is crucial for skin wound healing and reducing scars.
12 citations
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February 2025 in “Scientific Reports” MSC-EVs and UCB-EVs improve skin wound healing and reduce scarring.
8 citations
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July 2024 in “Scientific Reports” Salicylate helps wounds heal without scarring in mice.
1 citations
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January 2020 in “VTechWorks (Virginia Tech)” αCT1 improves scar appearance by changing early collagen structure.
October 1982 in “American Journal of Nursing” Wound healing is a complex process involving different cells and stages, leading to scar tissue formation and strength increase over time.
146 citations
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July 2018 in “Regenerative Medicine” Understanding different types of skin cells, especially fibroblasts, can lead to better treatments for wound healing and less scarring.
145 citations
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November 2018 in “Nature Communications” The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.
128 citations
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August 2020 in “Cell stem cell” Dermal fibroblasts have adjustable roles in wound healing, with specific cells promoting regeneration or scar formation.
61 citations
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September 2020 in “Bioactive Materials” A special dressing called FEA-PCEI can speed up wound healing, reduce scars, and help grow new hair follicles, but only at the right dosage.