163 citations
,
October 2001 in “EMBO journal” Overexpressing follistatin in mice delays wound healing and reduces scar size.
146 citations
,
July 2018 in “Regenerative Medicine” Understanding different types of skin cells, especially fibroblasts, can lead to better treatments for wound healing and less scarring.
145 citations
,
November 2018 in “Nature Communications” The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.
115 citations
,
December 2017 in “Wiley Interdisciplinary Reviews-Developmental Biology” Skin cells called dermal fibroblasts are important for skin growth, hair growth, and wound healing.
109 citations
,
December 2003 in “American Journal of Pathology” Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.
108 citations
,
January 2023 in “Journal of Tissue Engineering” Scarless skin repair is possible by understanding and balancing wound healing mechanisms.
99 citations
,
January 2002 in “Plastic & Reconstructive Surgery” Fetal rat wounds heal without scars at 16.5 days gestation.
89 citations
,
March 1990 in “PubMed” Shaving is the most effective temporary hair removal method for facial hirsutism.
78 citations
,
June 2021 in “Dermatology and Therapy” Future acne treatments should aggressively target inflammation to prevent scarring.
75 citations
,
January 2011 in “Plastic and Reconstructive Surgery” The dermal regeneration template is effective in skin regeneration, reducing scarring, and has potential for future improvements.
65 citations
,
June 2020 in “Stem Cell Research & Therapy” Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.
61 citations
,
September 2020 in “Bioactive Materials” A special dressing called FEA-PCEI can speed up wound healing, reduce scars, and help grow new hair follicles, but only at the right dosage.
60 citations
,
June 2019 in “Ageing Research Reviews” Fat from the body can help improve hair growth and scars when used in skin treatments.
53 citations
,
July 2018 in “Journal of cosmetic dermatology” Platelet-rich plasma may improve skin rejuvenation, hair growth, and scar treatment, but more large-scale trials are needed for stronger evidence.
51 citations
,
January 2004 in “Skin Pharmacology and Physiology” The document explains hair growth and shedding, factors affecting it, and methods to evaluate hair loss, emphasizing the importance of skin biopsy for diagnosis.
44 citations
,
June 2023 in “Cell Reports” IL-1 promotes fat cell growth in skin, while WNT inhibits it and encourages scar formation.
44 citations
,
April 2012 in “American Journal of Clinical Dermatology” Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.
41 citations
,
September 2017 in “Advanced Healthcare Materials” A special hydrogel helps heal skin without scars and regrows hair.
40 citations
,
June 2013 in “Molecular Pharmaceutics” The gelatin/β-TCP scaffold with nanoparticles improves wound healing and skin regeneration.
38 citations
,
December 2012 in “Journal of Cutaneous Pathology” EVG staining is a valuable, simple, and cost-effective method for diagnosing various skin conditions in dermatopathology.
32 citations
,
March 2014 in “PLOS ONE” Mice lacking fibromodulin have disrupted healing patterns, leading to abnormal skin repair and scarring.
32 citations
,
January 2006 in “Acta dermato-venereologica” SACUMAN, a rare condition causing hair loss without clear signs, is often misdiagnosed and needs scalp biopsies for accurate detection.
31 citations
,
December 2022 in “Cold Spring Harbor Perspectives in Biology” Understanding cell transitions can lead to better wound healing treatments.
31 citations
,
January 2019 in “Frontiers in Veterinary Science” Laser therapy improved surgical scar healing in dogs.
30 citations
,
May 2019 in “Medicinal Research Reviews” Combining stem cells and targeted treatments can improve muscle and skin healing after cleft repair.
29 citations
,
November 2014 in “Experimental Dermatology” Injecting alpha-melanocyte-stimulating hormone in mice improved skin healing and reduced scarring.
28 citations
,
August 2018 in “Dermatologic Surgery” Platelet-Rich Plasma (PRP) may help improve hair density in primary cicatricial alopecias (PCAs) patients, but more trials are needed to confirm its benefits.
28 citations
,
July 2011 in “Journal of Plastic Reconstructive and Aesthetic Surgery” A patient had skin tissue death at the hair removal site after a hair transplant, which was treated with surgery.
27 citations
,
July 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” Lasers have become precise tools in skin treatment and diagnosis, with ongoing advancements improving their effectiveness.
26 citations
,
July 2007 in “Wound Repair and Regeneration” MRL/MpJ mice heal burns slower with more scarring and less tissue regeneration than BALB/c mice.