33 citations
,
February 2019 in “Journal of Tissue Engineering and Regenerative Medicine” Platelet-Rich Plasma (PRP) shows promise for treating various skin conditions, but more research is needed to standardize its use.
Reprogramming adult fibroblasts may enable scar-free healing.
79 citations
,
January 2018 in “Wiley Interdisciplinary Reviews-Developmental Biology” Understanding how baby skin heals without scars could help develop treatments for adults to heal wounds without leaving scars.
8 citations
,
June 2022 in “International Journal of Molecular Sciences” Tiny particles called extracellular vesicles show promise for skin improvement and anti-aging in facial care but face challenges like low production and lack of research.
6 citations
,
June 2022 in “Frontiers in Bioengineering and Biotechnology” The gel with icariin speeds up wound healing, reduces scarring, and helps hair growth by controlling BMP4 signaling. It also reduces inflammation and improves wound quality in mice, adapts to different wound shapes, and gradually releases icariin to aid healing. It also prevents too much collagen and myofibroblast formation during skin healing.
4 citations
,
December 2022 in “Frontiers in Bioengineering and Biotechnology” Exosomes show promise for improving wound healing, reducing aging signs, preventing hair loss, and lightening skin but require more research and better production methods.
2 citations
,
April 2023 in “Stem Cell Research & Therapy” Tiny fat-derived particles can help repair soft tissues by changing immune cell types.
August 2023 in “Bioengineering” Bioprinting could greatly improve health outcomes but faces challenges like material choice and ensuring long-term survival of printed tissues.
January 2024 in “Advanced Science” New microspheres help heal skin wounds and regrow hair without scarring.
April 2018 in “Journal of Investigative Dermatology” Fetuin A, Anigozanthos Flavidus extract, and Ovol2 affect wound healing and skin regeneration.
1 citations
,
April 2023 in “Science Advances” High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.
132 citations
,
January 2017 in “International Journal of Molecular Sciences” Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
May 2025 in “International Journal of Molecular Sciences” Exosomes from rat hair follicle stem cells may help heal wounds and regenerate skin.
21 citations
,
July 2018 in “International Journal of Molecular Sciences” Foxn1 is crucial for skin development and healing, and altering its expression may aid regenerative medicine.
48 citations
,
January 2018 in “Stem Cells International” Skin-derived stem cells show promise for improving wound healing and creating transplantable tissue.
15 citations
,
August 2023 in “Journal of Nanobiotechnology” Nanotechnology could improve scar treatment but needs more development.
41 citations
,
August 2015 in “The FASEB Journal” Blocking the Wnt/β‐catenin pathway can speed up wound healing, reduce scarring, and improve cartilage repair.
July 2024 in “Journal Of Stem Cell Research” Mesenchymal stem cells improve skin appearance and structure in dermatology and aesthetic medicine.
28 citations
,
April 2023 in “Stem cell research & therapy” Tiny vesicles from stem cells could be a new treatment for healing wounds.
December 2025 in “MEDFARM Jurnal Farmasi dan Kesehatan” Topical metformin shows promise for treating skin conditions like acne and psoriasis.
47 citations
,
November 2012 in “Wound repair and regeneration” Nude mice with grafted human skin developed scars similar to human hypertrophic scars.
6 citations
,
September 2017 in “Experimental and Therapeutic Medicine” Shortened PEDF peptides speed up skin wound healing by boosting cell growth.
19 citations
,
November 2018 in “Experimental Dermatology” The spiny mouse can regenerate its skin without scarring, which could help us learn how to heal human skin better.
71 citations
,
February 2020 in “Journal of Translational Medicine” Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.
Fraser's Dolphin can heal skin wounds with minimal scarring, unlike humans.
359 citations
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January 2015 in “Cold Spring Harbor Perspectives in Medicine” Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.
8 citations
,
May 2021 in “Applied Materials Today” New nano composite helps reduce scars and regrow hair during burn wound healing.
202 citations
,
August 2007 in “Biomaterials” Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.
Elastin-like recombinamers show promise for better wound healing and skin regeneration.
19 citations
,
March 2017 in “PLoS ONE” PSU are better than THF at regenerating skin layers in lab models.