research Epidermal and Hair Follicle Progenitor Cells Express Melanoma-Associated Chondroitin Sulfate Proteoglycan Core Protein
MCSP may help identify and regulate skin stem cells, affecting hair growth and regeneration.
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research Isolation and Characterization of Cutaneous Epithelial Stem Cells
Scientists found ways to identify and collect skin stem cells, which vary by skin area and are delicate.
research Age-associated inflammation inhibits epidermal stem cell function
Aging causes skin stem cells to work less effectively.
research Single cell transcriptomics of human epidermis reveals basal stem cell transition states
Basal stem cells in the skin have distinct types that are crucial for skin structure and health.
research GLI2 Is Expressed in Normal Human Epidermis and BCC and Induces GLI1 Expression by Binding to its Promoter
GLI2 activates GLI1, promoting skin tumor growth and hair development.
research The chemokine SDF-1/CXCL12 regulates the migration of melanocyte progenitors in mouse hair follicles
SDF-1/CXCL12 and its receptor CXCR4 are crucial for melanocyte movement in mouse hair follicles.
research Intestinal Stem Cell Imaging in Colorectal Cancer Screening
Imaging intestinal stem cells might help detect early signs of colorectal cancer.
research Attraction of sensory fibers by Merkel cells during co-culture of sensory ganglia and hair follcies in collagen-gel
research Nestin expression in hair follicle sheath progenitor cells
Nestin is found in hair follicle progenitor cells, linking them to neural stem cells.
research Stem Cells in the Wild: Understanding the World of Stem Cells through Intravital Imaging
Intravital imaging helps us better understand stem cells in their natural environment and could improve knowledge of organ regeneration and cancer development.
research Advancing skin model development: A focus on a self-assembled, induced pluripotent stem cell-derived, xeno-free approach
A new ethical skin model using stem cells offers a reliable alternative for dermatological research.
research Role of -catenin in Epidermal Stem Cell Expansion, Lineage Selection, and Cancer
Beta-catenin is crucial for skin cell growth, development, and cancer formation.
research 320 Desmoglein 3-mediated mechanical transadhesion controls epithelial stem cell quiescence
Desmoglein 3 is important for keeping hair follicle stem cells inactive and maintaining their special properties.
research EGFR signaling is required for regenerative proliferation in the cochlea: Conservation in birds and mammals
EGFR signaling is essential for ear cell regeneration in both birds and mammals.
research MSC-derived exosomes protect auditory hair cells from neomycin-induced damage via autophagy regulation
Tiny particles from stem cells can help protect ear cells from antibiotic damage by helping cells remove damaged parts.
research miR ‐203a‐3p promotes loureirin A‐induced hair follicle stem cells differentiation by targeting Smad1
miR-203a-3p helps hair follicle stem cells become specialized by targeting Smad1.
research miR‐124 promotes neural differentiation in mouse bulge stem cells by repressing Ptbp1 and Sox9
miR-124 helps mouse hair follicle stem cells become nerve cells by blocking Ptbp1 and Sox9.
research Nestin‐positive hair follicle pluripotent stem cells can promote regeneration of impinged peripheral nerve injury
Hair follicle stem cells can help repair nerve injuries.
research Glycome profiling by lectin microarray reveals dynamic glycan alterations during epidermal stem cell aging
Aging changes sugar molecules on skin stem cells, which may affect their ability to repair skin.
research SOX2 in the Skin
SOX2 is crucial for skin cell function and hair growth, and it plays a role in skin cancer and wound healing.
research Advances in single-cell transcriptomics in animal research
Single-cell transcriptomics helps improve animal health and productivity by studying gene expression in individual cells.
research Epithelial-Mesenchymal Micro-niches Govern Stem Cell Lineage Choices
Different small areas within hair follicles send specific signals that control what type of cells stem cells become.
research Establishing an academic laboratory: mentoring as a business model
Valentina Greco emphasizes the importance of combining business management with mentoring to run a successful academic lab.
research Gate keeping the sebaceous gland
The research found that specific stem cells maintain skin gland openings and that disrupting their activity can cause blockages or early cancer signs, indicating a need for targeted treatments.
research A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease
Oncogenic melanocyte stem cells can develop into melanoma similar to human cases.
research Clinical Snippets
Some cells may slow melanoma growth, a protein could affect skin pigmentation, a gene-silencing method might treat hair defects, skin bacteria changes likely result from eczema, and a defensin protein could help treat multiple sclerosis.
research An in vivo comparative study of sonic, desert and Indian hedgehog reveals that hedgehog pathway activity regulates epidermal stem cell homeostasis
Proper hedgehog signaling is crucial for maintaining healthy skin stem cells.
research Abstract 5020: Characterization of epidermal stem cells in SKH1 hairless mice, a widely used mouse model to investigate ultraviolet radiation carcinogenesis.
SKH1 hairless mice have identifiable epidermal stem cells with specific markers.
research SCA-1+ Cells with an Adipocyte Phenotype in Neonatal Mouse Skin
Sca-1+ cells in newborn mouse skin may become fat cells.
research Single cell analysis of transcriptome and open chromatin reveals the dynamics of hair follicle stem cell aging
Hair follicle stem cells change states with age, affecting hair growth and aging.