research N-Acyl arylsulfonamides as novel, reversible inhibitors of human steroid sulfatase
Scientists found new, better-working inhibitors for a hormone-related enzyme.
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research US clinics marketing unproven and unlicensed adipose-derived autologous stem cell interventions
The document warns against US clinics selling untested stem cell treatments without FDA approval.
research Adipose-derived stromal vascular fraction (SVF) for the treatment of androgenic alopecia (AGA): a systematic review.
Fat stem cell treatment is safe and increases hair density for hair loss, but more research is needed.
research Effect of Compound Diandao Pulvis Drug Facial Mask on Acne Model of Rabbit's Ears
CDPDFM can improve acne symptoms in rabbit ears.
research Advancing fat graft survival: from adipose-derived stem cell mechanisms to next-generation regenerative strategies
Autologous fat grafting is popular in reconstructive and aesthetic surgery but faces challenges due to unpredictable graft resorption. Two cell-based approaches, stromal vascular fraction (SVF) and culture-expanded adipose-derived stem/stromal cells (ADSCs), have been developed to improve fat retention. Meta-analyses indicate that expanded ADSCs offer significantly better outcomes than SVF, due to their ability to support graft survival through growth factor secretion, immunomodulation, and other mechanisms. The review covers clinical evidence for ADSC- and SVF-enriched fat grafting across various applications, evaluates adjunctive strategies like platelet-rich plasma and exosome-based therapies, and highlights ongoing challenges such as the need for standardized preparation methods and safety assessments.